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Mechanisms of copper ion mediated Huntington's disease progression.
Fox JH, Kama JA, Lieberman G, Chopra R, Dorsey K, Chopra V, Volitakis I, Cherny RA, Bush AI, Hersch S. Fox JH, et al. PLoS One. 2007 Mar 28;2(3):e334. doi: 10.1371/journal.pone.0000334. PLoS One. 2007. PMID: 17396163 Free PMC article.
The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease.
Fox JH, Connor T, Chopra V, Dorsey K, Kama JA, Bleckmann D, Betschart C, Hoyer D, Frentzel S, Difiglia M, Paganetti P, Hersch SM. Fox JH, et al. Mol Neurodegener. 2010 Jun 22;5:26. doi: 10.1186/1750-1326-5-26. Mol Neurodegener. 2010. PMID: 20569486 Free PMC article.
128 results