BNP-guided vs symptom-guided heart failure therapy: the Trial of Intensified vs Standard Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF) randomized trial.
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JAMA. 2009 Jan 28;301(4):383-92. doi: 10.1001/jama.2009.2.
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PMID: 19176440
Clinical Trial.