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AKR1B7 is induced by the farnesoid X receptor and metabolizes bile acids.
Schmidt DR, Schmidt S, Holmstrom SR, Makishima M, Yu RT, Cummins CL, Mangelsdorf DJ, Kliewer SA. Schmidt DR, et al. Among authors: cummins cl. J Biol Chem. 2011 Jan 28;286(4):2425-32. doi: 10.1074/jbc.M110.181230. Epub 2010 Nov 16. J Biol Chem. 2011. PMID: 21081494 Free PMC article.
Regulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: putative role of LXRs in lipid detoxification processes.
Volle DH, Repa JJ, Mazur A, Cummins CL, Val P, Henry-Berger J, Caira F, Veyssiere G, Mangelsdorf DJ, Lobaccaro JM. Volle DH, et al. Among authors: cummins cl. Mol Endocrinol. 2004 Apr;18(4):888-98. doi: 10.1210/me.2003-0338. Epub 2004 Jan 22. Mol Endocrinol. 2004. PMID: 14739254
96 results