Grünert R - Search Results

1

Synthesis of bicyclic sigma receptor ligands with cytotoxic activity.

Geiger C, Zelenka C, Weigl M, Fröhlich R, Wibbeling B, Lehmkuhl K, Schepmann D, Grünert R, Bednarski PJ, Wünsch B. Geiger C, et al. Among authors: grunert r. J Med Chem. 2007 Nov 29;50(24):6144-53. doi: 10.1021/jm070620b. Epub 2007 Oct 30. J Med Chem. 2007. PMID: 17967001

2

2,4-Diamino-9H-pyrimido[4,5-b]indol-5-ols: synthesis, in vitro cytotoxic activity, and QSAR investigations.

Dotzauer B, Grünert R, Bednarski PJ, Lanig H, Landwehr J, Troschütz R. Dotzauer B, et al. Among authors: grunert r. Bioorg Med Chem. 2006 Nov 1;14(21):7282-92. doi: 10.1016/j.bmc.2006.06.051. Epub 2006 Jul 14. Bioorg Med Chem. 2006. PMID: 16843672

3

Relationships between the structure of 6-allyl-6,8-diazabicyclo[3.2.2]nonane derivatives and their sigma receptor affinity and cytotoxic activity.

Holl R, Schepmann D, Grünert R, Bednarski PJ, Wünsch B. Holl R, et al. Among authors: grunert r. Bioorg Med Chem. 2009 Jan 15;17(2):777-93. doi: 10.1016/j.bmc.2008.11.043. Epub 2008 Nov 24. Bioorg Med Chem. 2009. PMID: 19081725

4

Relationships between the structure of 6-substituted 6,8-diazabicyclo[3.2.2]nonan-2-ones and their sigma receptor affinity and cytotoxic activity.

Holl R, Schepmann D, Bednarski PJ, Grünert R, Wünsch B. Holl R, et al. Among authors: grunert r. Bioorg Med Chem. 2009 Feb 15;17(4):1445-55. doi: 10.1016/j.bmc.2009.01.012. Epub 2009 Jan 15. Bioorg Med Chem. 2009. PMID: 19196515

5

Dancing of the second aromatic residue around the 6,8-diazabicyclo[3.2.2]nonane framework: influence on sigma receptor affinity and cytotoxicity.

Holl R, Schepmann D, Fröhlich R, Grünert R, Bednarski PJ, Wünsch B. Holl R, et al. Among authors: grunert r. J Med Chem. 2009 Apr 9;52(7):2126-37. doi: 10.1021/jm801522j. J Med Chem. 2009. PMID: 19243173

6

Synthesis and cytotoxic activity of 5,6-heteroaromatically annulated pyridine-2,4-diamines.

Willemann C, Grünert R, Bednarski PJ, Troschütz R. Willemann C, et al. Among authors: grunert r. Bioorg Med Chem. 2009 Jul 1;17(13):4406-19. doi: 10.1016/j.bmc.2009.05.016. Epub 2009 May 12. Bioorg Med Chem. 2009. PMID: 19481463

7

Synthesis, X-ray crystal structures, stabilities, and in vitro cytotoxic activities of new heteroarylacrylonitriles.

Saczewski F, Reszka P, Gdaniec M, Grünert R, Bednarski PJ. Saczewski F, et al. Among authors: grunert r. J Med Chem. 2004 Jun 17;47(13):3438-49. doi: 10.1021/jm0311036. J Med Chem. 2004. PMID: 15189040

8

Synthesis, structural characterization, and in vitro antitumor activity of novel N-(6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)arylsulfonamides.

Brzozowski Z, Saczewski F, Sławiński J, Bednarski PJ, Grünert R, Gdaniec M. Brzozowski Z, et al. Among authors: grunert r. Bioorg Med Chem. 2007 Apr 1;15(7):2560-72. doi: 10.1016/j.bmc.2007.01.052. Epub 2007 Feb 2. Bioorg Med Chem. 2007. PMID: 17306551

9

Synthesis and pharmacological evaluation of SNC80 analogues with a bridged piperazine ring.

Holl R, Jung B, Schepmann D, Humpf HU, Grünert R, Bednarski PJ, Englberger W, Wünsch B. Holl R, et al. Among authors: grunert r. ChemMedChem. 2009 Dec;4(12):2111-22. doi: 10.1002/cmdc.200900358. ChemMedChem. 2009. PMID: 19827086

10

In vitro anticancer activity and evaluation of DNA duplex binding affinity of phenyl-substituted indoloquinolines.

Riechert-Krause F, Eick A, Grünert R, Bednarski PJ, Weisz K. Riechert-Krause F, et al. Among authors: grunert r. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2380-3. doi: 10.1016/j.bmcl.2011.02.088. Epub 2011 Feb 26. Bioorg Med Chem Lett. 2011. PMID: 21414783

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