McEwan DG - Search Results

1

Src kinase modulates the activation, transport and signalling dynamics of fibroblast growth factor receptors.

Sandilands E, Akbarzadeh S, Vecchione A, McEwan DG, Frame MC, Heath JK. Sandilands E, et al. Among authors: mcewan dg. EMBO Rep. 2007 Dec;8(12):1162-9. doi: 10.1038/sj.embor.7401097. Epub 2007 Nov 2. EMBO Rep. 2007. PMID: 17975556 Free PMC article.

2

Chemoresistant KM12C colon cancer cells are addicted to low cyclic AMP levels in a phosphodiesterase 4-regulated compartment via effects on phosphoinositide 3-kinase.

McEwan DG, Brunton VG, Baillie GS, Leslie NR, Houslay MD, Frame MC. McEwan DG, et al. Cancer Res. 2007 Jun 1;67(11):5248-57. doi: 10.1158/0008-5472.CAN-07-0097. Cancer Res. 2007. PMID: 17545604

3

Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling.

Sandilands E, Serrels B, McEwan DG, Morton JP, Macagno JP, McLeod K, Stevens C, Brunton VG, Langdon WY, Vidal M, Sansom OJ, Dikic I, Wilkinson S, Frame MC. Sandilands E, et al. Among authors: mcewan dg. Nat Cell Biol. 2011 Dec 4;14(1):51-60. doi: 10.1038/ncb2386. Nat Cell Biol. 2011. PMID: 22138575

4

A conserved ATG2-GABARAP family interaction is critical for phagophore formation.

Bozic M, van den Bekerom L, Milne BA, Goodman N, Roberston L, Prescott AR, Macartney TJ, Dawe N, McEwan DG. Bozic M, et al. Among authors: mcewan dg. EMBO Rep. 2020 Mar 4;21(3):e48412. doi: 10.15252/embr.201948412. Epub 2020 Feb 3. EMBO Rep. 2020. PMID: 32009292 Free PMC article.

5

The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathways.

Gubas A, Karantanou C, Popovic D, Tascher G, Hoffmann ME, Platzek A, Dawe N, Dikic I, Krause DS, McEwan DG. Gubas A, et al. Among authors: mcewan dg. FEBS Lett. 2021 Apr;595(7):864-880. doi: 10.1002/1873-3468.14041. Epub 2021 Feb 28. FEBS Lett. 2021. PMID: 33452816 Free article.

6

DRAM-4 and DRAM-5 are compensatory regulators of autophagy and cell survival in nutrient-deprived conditions.

Barthet VJA, Mrschtik M, Kania E, McEwan DG, Croft D, O'Prey J, Long JS, Ryan KM. Barthet VJA, et al. Among authors: mcewan dg. FEBS J. 2022 Jul;289(13):3752-3769. doi: 10.1111/febs.16365. Epub 2022 Feb 4. FEBS J. 2022. PMID: 35060334 Free PMC article.

7

Nix is a selective autophagy receptor for mitochondrial clearance.

Novak I, Kirkin V, McEwan DG, Zhang J, Wild P, Rozenknop A, Rogov V, Löhr F, Popovic D, Occhipinti A, Reichert AS, Terzic J, Dötsch V, Ney PA, Dikic I. Novak I, et al. Among authors: mcewan dg. EMBO Rep. 2010 Jan;11(1):45-51. doi: 10.1038/embor.2009.256. Epub 2009 Dec 11. EMBO Rep. 2010. PMID: 20010802 Free PMC article.

8

Structural and functional analysis of the GABARAP interaction motif (GIM).

Rogov VV, Stolz A, Ravichandran AC, Rios-Szwed DO, Suzuki H, Kniss A, Löhr F, Wakatsuki S, Dötsch V, Dikic I, Dobson RC, McEwan DG. Rogov VV, et al. Among authors: mcewan dg. EMBO Rep. 2017 Aug;18(8):1382-1396. doi: 10.15252/embr.201643587. Epub 2017 Jun 27. EMBO Rep. 2017. PMID: 28655748 Free PMC article.

9

Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2.

Bolger GB, Peden AH, Steele MR, MacKenzie C, McEwan DG, Wallace DA, Huston E, Baillie GS, Houslay MD. Bolger GB, et al. Among authors: mcewan dg. J Biol Chem. 2003 Aug 29;278(35):33351-63. doi: 10.1074/jbc.M303269200. Epub 2003 Jun 16. J Biol Chem. 2003. PMID: 12810716 Free article.

10

A role for NBR1 in autophagosomal degradation of ubiquitinated substrates.

Kirkin V, Lamark T, Sou YS, Bjørkøy G, Nunn JL, Bruun JA, Shvets E, McEwan DG, Clausen TH, Wild P, Bilusic I, Theurillat JP, Øvervatn A, Ishii T, Elazar Z, Komatsu M, Dikic I, Johansen T. Kirkin V, et al. Among authors: mcewan dg. Mol Cell. 2009 Feb 27;33(4):505-16. doi: 10.1016/j.molcel.2009.01.020. Mol Cell. 2009. PMID: 19250911 Free article.

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