Heinen S - Search Results

1

Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency.

Józsi M, Licht C, Strobel S, Zipfel SL, Richter H, Heinen S, Zipfel PF, Skerka C. Józsi M, et al. Among authors: heinen s. Blood. 2008 Feb 1;111(3):1512-4. doi: 10.1182/blood-2007-09-109876. Epub 2007 Nov 15. Blood. 2008. PMID: 18006700 Free article.

2

Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome.

Manuelian T, Hellwage J, Meri S, Caprioli J, Noris M, Heinen S, Jozsi M, Neumann HP, Remuzzi G, Zipfel PF. Manuelian T, et al. Among authors: heinen s. J Clin Invest. 2003 Apr;111(8):1181-90. doi: 10.1172/JCI16651. J Clin Invest. 2003. PMID: 12697737 Free PMC article.

3

Complement and diseases: defective alternative pathway control results in kidney and eye diseases.

Zipfel PF, Heinen S, Józsi M, Skerka C. Zipfel PF, et al. Among authors: heinen s. Mol Immunol. 2006 Jan;43(1-2):97-106. doi: 10.1016/j.molimm.2005.06.015. Mol Immunol. 2006. PMID: 16026839 Review.

4

Factor H and atypical hemolytic uremic syndrome: mutations in the C-terminus cause structural changes and defective recognition functions.

Józsi M, Heinen S, Hartmann A, Ostrowicz CW, Hälbich S, Richter H, Kunert A, Licht C, Saunders RE, Perkins SJ, Zipfel PF, Skerka C. Józsi M, et al. Among authors: heinen s. J Am Soc Nephrol. 2006 Jan;17(1):170-7. doi: 10.1681/ASN.2005080868. Epub 2005 Dec 7. J Am Soc Nephrol. 2006. PMID: 16338962

5

De novo gene conversion in the RCA gene cluster (1q32) causes mutations in complement factor H associated with atypical hemolytic uremic syndrome.

Heinen S, Sanchez-Corral P, Jackson MS, Strain L, Goodship JA, Kemp EJ, Skerka C, Jokiranta TS, Meyers K, Wagner E, Robitaille P, Esparza-Gordillo J, Rodriguez de Cordoba S, Zipfel PF, Goodship TH. Heinen S, et al. Hum Mutat. 2006 Mar;27(3):292-3. doi: 10.1002/humu.9408. Hum Mutat. 2006. PMID: 16470555

6

Hemolytic uremic syndrome: a factor H mutation (E1172Stop) causes defective complement control at the surface of endothelial cells.

Heinen S, Józsi M, Hartmann A, Noris M, Remuzzi G, Skerka C, Zipfel PF. Heinen S, et al. J Am Soc Nephrol. 2007 Feb;18(2):506-14. doi: 10.1681/ASN.2006091069. Epub 2007 Jan 17. J Am Soc Nephrol. 2007. PMID: 17229916

7

Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome.

Zipfel PF, Edey M, Heinen S, Józsi M, Richter H, Misselwitz J, Hoppe B, Routledge D, Strain L, Hughes AE, Goodship JA, Licht C, Goodship TH, Skerka C. Zipfel PF, et al. Among authors: heinen s. PLoS Genet. 2007 Mar 16;3(3):e41. doi: 10.1371/journal.pgen.0030041. Epub 2007 Feb 1. PLoS Genet. 2007. PMID: 17367211 Free PMC article.

8

Factor H dysfunction in patients with atypical hemolytic uremic syndrome contributes to complement deposition on platelets and their activation.

Ståhl AL, Vaziri-Sani F, Heinen S, Kristoffersson AC, Gydell KH, Raafat R, Gutierrez A, Beringer O, Zipfel PF, Karpman D. Ståhl AL, et al. Among authors: heinen s. Blood. 2008 Jun 1;111(11):5307-15. doi: 10.1182/blood-2007-08-106153. Epub 2008 Feb 11. Blood. 2008. PMID: 18268093 Free article.

9

Heinen S, Hartmann A, Lauer N, Wiehl U, Dahse HM, Schirmer S, Gropp K, Enghardt T, Wallich R, Hälbich S, Mihlan M, Schlötzer-Schrehardt U, Zipfel PF, Skerka C. Heinen S, et al. Blood. 2009 Sep 17;114(12):2439-47. doi: 10.1182/blood-2009-02-205641. Epub 2009 Jun 15. Blood. 2009. PMID: 19528535 Free article.

10

Thrombotic microangiopathies: new insights and new challenges.

Zipfel PF, Heinen S, Skerka C. Zipfel PF, et al. Among authors: heinen s. Curr Opin Nephrol Hypertens. 2010 Jul;19(4):372-8. doi: 10.1097/MNH.0b013e32833aff4a. Curr Opin Nephrol Hypertens. 2010. PMID: 20539230 Review.

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