Kelliher MA - Search Results

1

RIP1 links inflammatory and growth factor signaling pathways by regulating expression of the EGFR.

Ramnarain DB, Paulmurugan R, Park S, Mickey BE, Asaithamby A, Saha D, Kelliher MA, Mukhopadhyay P, Banani F, Madden CJ, Wright PS, Chakravarty S, Habib AA. Ramnarain DB, et al. Among authors: kelliher ma. Cell Death Differ. 2008 Feb;15(2):344-53. doi: 10.1038/sj.cdd.4402268. Epub 2007 Nov 16. Cell Death Differ. 2008. PMID: 18007664

2

TBK1 inhibition unleashes RIPK1, resensitizing tumors to immunotherapy.

Kelliher MA, Fitzgerald KA. Kelliher MA, et al. Trends Immunol. 2023 Mar;44(3):156-158. doi: 10.1016/j.it.2023.01.009. Epub 2023 Feb 4. Trends Immunol. 2023. PMID: 36740513

3

RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3.

Dillon CP, Weinlich R, Rodriguez DA, Cripps JG, Quarato G, Gurung P, Verbist KC, Brewer TL, Llambi F, Gong YN, Janke LJ, Kelliher MA, Kanneganti TD, Green DR. Dillon CP, et al. Among authors: kelliher ma. Cell. 2014 May 22;157(5):1189-202. doi: 10.1016/j.cell.2014.04.018. Epub 2014 May 8. Cell. 2014. PMID: 24813850 Free PMC article.

4

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation.

Meylan E, Burns K, Hofmann K, Blancheteau V, Martinon F, Kelliher M, Tschopp J. Meylan E, et al. Nat Immunol. 2004 May;5(5):503-7. doi: 10.1038/ni1061. Epub 2004 Apr 4. Nat Immunol. 2004. PMID: 15064760

5

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis.

Kondylis V, Polykratis A, Ehlken H, Ochoa-Callejero L, Straub BK, Krishna-Subramanian S, Van TM, Curth HM, Heise N, Weih F, Klein U, Schirmacher P, Kelliher M, Pasparakis M. Kondylis V, et al. Cancer Cell. 2015 Nov 9;28(5):582-598. doi: 10.1016/j.ccell.2015.10.001. Cancer Cell. 2015. PMID: 26555174 Free PMC article.

6

RIPK1 mediates a disease-associated microglial response in Alzheimer's disease.

Ofengeim D, Mazzitelli S, Ito Y, DeWitt JP, Mifflin L, Zou C, Das S, Adiconis X, Chen H, Zhu H, Kelliher MA, Levin JZ, Yuan J. Ofengeim D, et al. Among authors: kelliher ma. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8788-E8797. doi: 10.1073/pnas.1714175114. Epub 2017 Sep 13. Proc Natl Acad Sci U S A. 2017. PMID: 28904096 Free PMC article.

7

The death domain kinase RIP1 is essential for tumor necrosis factor alpha signaling to p38 mitogen-activated protein kinase.

Lee TH, Huang Q, Oikemus S, Shank J, Ventura JJ, Cusson N, Vaillancourt RR, Su B, Davis RJ, Kelliher MA. Lee TH, et al. Among authors: kelliher ma. Mol Cell Biol. 2003 Nov;23(22):8377-85. doi: 10.1128/MCB.23.22.8377-8385.2003. Mol Cell Biol. 2003. PMID: 14585994 Free PMC article.

8

The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2.

Lee TH, Shank J, Cusson N, Kelliher MA. Lee TH, et al. Among authors: kelliher ma. J Biol Chem. 2004 Aug 6;279(32):33185-91. doi: 10.1074/jbc.M404206200. Epub 2004 Jun 1. J Biol Chem. 2004. PMID: 15175328 Free article.

9

A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage.

Yang Y, Xia F, Hermance N, Mabb A, Simonson S, Morrissey S, Gandhi P, Munson M, Miyamoto S, Kelliher MA. Yang Y, et al. Among authors: kelliher ma. Mol Cell Biol. 2011 Jul;31(14):2774-86. doi: 10.1128/MCB.01139-10. Epub 2011 May 23. Mol Cell Biol. 2011. PMID: 21606198 Free PMC article.

10

RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.

Lukens JR, Vogel P, Johnson GR, Kelliher MA, Iwakura Y, Lamkanfi M, Kanneganti TD. Lukens JR, et al. Among authors: kelliher ma. Nature. 2013 Jun 13;498(7453):224-7. doi: 10.1038/nature12174. Epub 2013 May 26. Nature. 2013. PMID: 23708968 Free PMC article.

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