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Agonists of peroxisome proliferators-activated receptors (PPAR) alpha, beta/delta or gamma reduce transforming growth factor (TGF)-beta-induced proteoglycans' production in chondrocytes.
Poleni PE, Bianchi A, Etienne S, Koufany M, Sebillaud S, Netter P, Terlain B, Jouzeau JY. Poleni PE, et al. Among authors: sebillaud s. Osteoarthritis Cartilage. 2007 May;15(5):493-505. doi: 10.1016/j.joca.2006.10.009. Epub 2006 Nov 29. Osteoarthritis Cartilage. 2007. PMID: 17140817 Free article.
Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14prostaglandin J2.
Bianchi A, Moulin D, Sebillaud S, Koufany M, Galteau MM, Netter P, Terlain B, Jouzeau JY. Bianchi A, et al. Among authors: sebillaud s. Arthritis Res Ther. 2005;7(6):R1325-37. doi: 10.1186/ar1830. Epub 2005 Sep 22. Arthritis Res Ther. 2005. PMID: 16277686 Free PMC article.
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