Kowalczyk R - Search Results

1

Synthesis of fluorescein-labelled O-mannosylated peptides as components for synthetic vaccines: comparison of two synthetic strategies.

Brimble MA, Kowalczyk R, Harris PW, Dunbar PR, Muir VJ. Brimble MA, et al. Among authors: kowalczyk r. Org Biomol Chem. 2008 Jan 7;6(1):112-21. doi: 10.1039/b712926b. Epub 2007 Oct 26. Org Biomol Chem. 2008. PMID: 18075655

2

A comparative study of different glycosylation methods for the synthesis of D-mannopyranosides of Nalpha-fluorenylmethoxycarbonyl-trans-4-hydroxy-L-proline allyl ester.

Lee DJ, Kowalczyk R, Muir VJ, Rendle PM, Brimble MA. Lee DJ, et al. Among authors: kowalczyk r. Carbohydr Res. 2007 Dec 10;342(17):2628-34. doi: 10.1016/j.carres.2007.08.015. Epub 2007 Aug 29. Carbohydr Res. 2007. PMID: 17854783

3

Synthesis of mannosylated glycopeptides as components for synthetic vaccines.

Kowalczyk R, Brimble MA, Dunbar R. Kowalczyk R, et al. Adv Exp Med Biol. 2009;611:351-2. doi: 10.1007/978-0-387-73657-0_155. Adv Exp Med Biol. 2009. PMID: 19400222 No abstract available.

4

Synthesis and evaluation of disulfide bond mimetics of amylin-(1-8) as agents to treat osteoporosis.

Kowalczyk R, Harris PW, Brimble MA, Callon KE, Watson M, Cornish J. Kowalczyk R, et al. Bioorg Med Chem. 2012 Apr 15;20(8):2661-8. doi: 10.1016/j.bmc.2012.02.030. Epub 2012 Feb 20. Bioorg Med Chem. 2012. PMID: 22398258

5

A simple solid phase, peptide-based fluorescent assay for the efficient and universal screening of HRV 3C protease inhibitors.

Schünemann K, Connelly S, Kowalczyk R, Sperry J, Wilson IA, Fraser JD, Brimble MA. Schünemann K, et al. Among authors: kowalczyk r. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5018-24. doi: 10.1016/j.bmcl.2012.06.015. Epub 2012 Jun 15. Bioorg Med Chem Lett. 2012. PMID: 22763202

6

How to blast osteoblasts? Novel dicarba analogues of amylin-(1-8) to treat osteoporosis.

Kowalczyk R, Brimble MA, Callon KE, Watson M, Cornish J. Kowalczyk R, et al. Bioorg Med Chem. 2012 Oct 15;20(20):6011-8. doi: 10.1016/j.bmc.2012.08.053. Epub 2012 Sep 7. Bioorg Med Chem. 2012. PMID: 22998786

7

Structure-activity relationships of the N-terminus of calcitonin gene-related peptide: key roles of alanine-5 and threonine-6 in receptor activation.

Hay DL, Harris PW, Kowalczyk R, Brimble MA, Rathbone DL, Barwell J, Conner AC, Poyner DR. Hay DL, et al. Among authors: kowalczyk r. Br J Pharmacol. 2014 Jan;171(2):415-26. doi: 10.1111/bph.12464. Br J Pharmacol. 2014. PMID: 24125506 Free PMC article.

8

An important side reaction using the thiol, 3,6-dioxa-1,8-octanedithiol (DODT), in 9-fluorenylmethoxycarbonyl-based solid phase peptide synthesis.

Harris PW, Kowalczyk R, Yang SH, Williams GM, Brimble MA. Harris PW, et al. Among authors: kowalczyk r. J Pept Sci. 2014 Mar;20(3):186-90. doi: 10.1002/psc.2595. Epub 2013 Dec 18. J Pept Sci. 2014. PMID: 24353069

9

Synthesis of truncated analogues of preptin-(1–16), and investigation of their ability to stimulate osteoblast proliferation.

Kowalczyk R, Yang SH, Brimble MA, Callon KE, Watson M, Park YE, Cornish J. Kowalczyk R, et al. Bioorg Med Chem. 2014 Jul 15;22(14):3565-72. doi: 10.1016/j.bmc.2014.05.026. Bioorg Med Chem. 2014. PMID: 24932835

10

Convergent chemoenzymatic synthesis of a library of glycosylated analogues of pramlintide: structure-activity relationships for amylin receptor agonism.

Kowalczyk R, Brimble MA, Tomabechi Y, Fairbanks AJ, Fletcher M, Hay DL. Kowalczyk R, et al. Org Biomol Chem. 2014 Nov 7;12(41):8142-51. doi: 10.1039/c4ob01208a. Epub 2014 Jul 17. Org Biomol Chem. 2014. PMID: 25030939

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