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Interleukin-4 inhibition of osteoclast differentiation is stronger than that of interleukin-13 and they are equivalent for induction of osteoprotegerin production from osteoblasts.
Yamada A, Takami M, Kawawa T, Yasuhara R, Zhao B, Mochizuki A, Miyamoto Y, Eto T, Yasuda H, Nakamichi Y, Kim N, Katagiri T, Suda T, Kamijo R. Yamada A, et al. Among authors: zhao b. Immunology. 2007 Apr;120(4):573-9. doi: 10.1111/j.1365-2567.2006.02538.x. Immunology. 2007. PMID: 17343616 Free PMC article.
IFN-gamma down-regulates Secretoglobin 3A1 gene expression.
Yamada A, Suzuki D, Miyazono A, Oshima K, Kamiya A, Zhao B, Takami M, Donnelly RP, Itabe H, Yamamoto M, Kimura S, Kamijo R. Yamada A, et al. Among authors: zhao b. Biochem Biophys Res Commun. 2009 Feb 20;379(4):964-8. doi: 10.1016/j.bbrc.2008.12.187. Epub 2009 Jan 9. Biochem Biophys Res Commun. 2009. PMID: 19135978 Free PMC article.
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