Leverkus M - Search Results

1

Suppression of cFLIP is sufficient to sensitize human melanoma cells to TRAIL- and CD95L-mediated apoptosis.

Geserick P, Drewniok C, Hupe M, Haas TL, Diessenbacher P, Sprick MR, Schön MP, Henkler F, Gollnick H, Walczak H, Leverkus M. Geserick P, et al. Among authors: leverkus m. Oncogene. 2008 May 15;27(22):3211-20. doi: 10.1038/sj.onc.1210985. Epub 2007 Dec 17. Oncogene. 2008. PMID: 18084329

2

NF-kappaB inhibition reveals differential mechanisms of TNF versus TRAIL-induced apoptosis upstream or at the level of caspase-8 activation independent of cIAP2.

Diessenbacher P, Hupe M, Sprick MR, Kerstan A, Geserick P, Haas TL, Wachter T, Neumann M, Walczak H, Silke J, Leverkus M. Diessenbacher P, et al. Among authors: leverkus m. J Invest Dermatol. 2008 May;128(5):1134-47. doi: 10.1038/sj.jid.5701141. Epub 2007 Nov 8. J Invest Dermatol. 2008. PMID: 17989734 Free article.

3

FLIP ing the coin? Death receptor-mediated signals during skin tumorigenesis.

Leverkus M, Diessenbacher P, Geserick P. Leverkus M, et al. Exp Dermatol. 2008 Jul;17(7):614-22. doi: 10.1111/j.1600-0625.2008.00728.x. Exp Dermatol. 2008. PMID: 18558995

4

The contact allergen nickel sensitizes primary human endothelial cells and keratinocytes to TRAIL-mediated apoptosis.

Schmidt M, Hupe M, Endres N, Raghavan B, Kavuri S, Geserick P, Goebeler M, Leverkus M. Schmidt M, et al. Among authors: leverkus m. J Cell Mol Med. 2010 Jun;14(6B):1760-76. doi: 10.1111/j.1582-4934.2009.00823.x. Epub 2009 Jun 16. J Cell Mol Med. 2010. PMID: 19538462 Free PMC article.

5

TRAIL-induced apoptosis and gene induction in HaCaT keratinocytes: differential contribution of TRAIL receptors 1 and 2.

Leverkus M, Sprick MR, Wachter T, Denk A, Bröcker EB, Walczak H, Neumann M. Leverkus M, et al. J Invest Dermatol. 2003 Jul;121(1):149-55. doi: 10.1046/j.1523-1747.2003.12332.x. J Invest Dermatol. 2003. PMID: 12839575 Free article.

6

cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes.

Wachter T, Sprick M, Hausmann D, Kerstan A, McPherson K, Stassi G, Bröcker EB, Walczak H, Leverkus M. Wachter T, et al. Among authors: leverkus m. J Biol Chem. 2004 Dec 17;279(51):52824-34. doi: 10.1074/jbc.M409554200. Epub 2004 Sep 30. J Biol Chem. 2004. PMID: 15459191 Free article.

7

Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment.

Geserick P, Hupe M, Moulin M, Wong WW, Feoktistova M, Kellert B, Gollnick H, Silke J, Leverkus M. Geserick P, et al. Among authors: leverkus m. J Cell Biol. 2009 Dec 28;187(7):1037-54. doi: 10.1083/jcb.200904158. J Cell Biol. 2009. PMID: 20038679 Free PMC article.

8

Cellular FLICE-inhibitory protein (cFLIP) isoforms block CD95- and TRAIL death receptor-induced gene induction irrespective of processing of caspase-8 or cFLIP in the death-inducing signaling complex.

Kavuri SM, Geserick P, Berg D, Dimitrova DP, Feoktistova M, Siegmund D, Gollnick H, Neumann M, Wajant H, Leverkus M. Kavuri SM, et al. Among authors: leverkus m. J Biol Chem. 2011 May 13;286(19):16631-46. doi: 10.1074/jbc.M110.148585. Epub 2011 Mar 22. J Biol Chem. 2011. PMID: 21454681 Free PMC article.

9

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms.

Feoktistova M, Geserick P, Kellert B, Dimitrova DP, Langlais C, Hupe M, Cain K, MacFarlane M, Häcker G, Leverkus M. Feoktistova M, et al. Among authors: leverkus m. Mol Cell. 2011 Aug 5;43(3):449-63. doi: 10.1016/j.molcel.2011.06.011. Epub 2011 Jul 7. Mol Cell. 2011. PMID: 21737330 Free PMC article.

10

Pick your poison: the Ripoptosome, a cell death platform regulating apoptosis and necroptosis.

Feoktistova M, Geserick P, Panayotova-Dimitrova D, Leverkus M. Feoktistova M, et al. Among authors: leverkus m. Cell Cycle. 2012 Feb 1;11(3):460-7. doi: 10.4161/cc.11.3.19060. Epub 2012 Feb 1. Cell Cycle. 2012. PMID: 22274400

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