Lock R - Search Results

1

Initial testing (stage 1) of the BH3 mimetic ABT-263 by the pediatric preclinical testing program.

Lock R, Carol H, Houghton PJ, Morton CL, Kolb EA, Gorlick R, Reynolds CP, Maris JM, Keir ST, Wu J, Smith MA. Lock R, et al. Pediatr Blood Cancer. 2008 Jun;50(6):1181-9. doi: 10.1002/pbc.21433. Pediatr Blood Cancer. 2008. PMID: 18085673

2

Testing of new agents in childhood cancer preclinical models: meeting summary.

Houghton PJ, Adamson PC, Blaney S, Fine HA, Gorlick R, Haber M, Helman L, Hirschfeld S, Hollingshead MG, Israel MA, Lock RB, Maris JM, Merlino G, Patterson W, Reynolds CP, Shannon K, Yu A, Yu J, Smith MA. Houghton PJ, et al. Among authors: lock rb. Clin Cancer Res. 2002 Dec;8(12):3646-57. Clin Cancer Res. 2002. PMID: 12473573

3

Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies.

Liem NL, Papa RA, Milross CG, Schmid MA, Tajbakhsh M, Choi S, Ramirez CD, Rice AM, Haber M, Norris MD, MacKenzie KL, Lock RB. Liem NL, et al. Blood. 2004 May 15;103(10):3905-14. doi: 10.1182/blood-2003-08-2911. Epub 2004 Feb 5. Blood. 2004. PMID: 14764536 Free article.

4

Dexamethasone resistance in B-cell precursor childhood acute lymphoblastic leukemia occurs downstream of ligand-induced nuclear translocation of the glucocorticoid receptor.

Bachmann PS, Gorman R, Mackenzie KL, Lutze-Mann L, Lock RB. Bachmann PS, et al. Among authors: lock rb. Blood. 2005 Mar 15;105(6):2519-26. doi: 10.1182/blood-2004-05-2023. Epub 2004 Nov 30. Blood. 2005. PMID: 15572593 Free article.

5

The pediatric preclinical testing program: description of models and early testing results.

Houghton PJ, Morton CL, Tucker C, Payne D, Favours E, Cole C, Gorlick R, Kolb EA, Zhang W, Lock R, Carol H, Tajbakhsh M, Reynolds CP, Maris JM, Courtright J, Keir ST, Friedman HS, Stopford C, Zeidner J, Wu J, Liu T, Billups CA, Khan J, Ansher S, Zhang J, Smith MA. Houghton PJ, et al. Among authors: lock r. Pediatr Blood Cancer. 2007 Dec;49(7):928-40. doi: 10.1002/pbc.21078. Pediatr Blood Cancer. 2007. PMID: 17066459

6

Credentialing preclinical pediatric xenograft models using gene expression and tissue microarray analysis.

Whiteford CC, Bilke S, Greer BT, Chen Q, Braunschweig TA, Cenacchi N, Wei JS, Smith MA, Houghton P, Morton C, Reynolds CP, Lock R, Gorlick R, Khanna C, Thiele CJ, Takikita M, Catchpoole D, Hewitt SM, Khan J. Whiteford CC, et al. Among authors: lock r. Cancer Res. 2007 Jan 1;67(1):32-40. doi: 10.1158/0008-5472.CAN-06-0610. Cancer Res. 2007. PMID: 17210681

7

Initial testing (stage 1) of the proteasome inhibitor bortezomib by the pediatric preclinical testing program.

Houghton PJ, Morton CL, Kolb EA, Lock R, Carol H, Reynolds CP, Keshelava N, Maris JM, Keir ST, Wu J, Smith MA. Houghton PJ, et al. Among authors: lock r. Pediatr Blood Cancer. 2008 Jan;50(1):37-45. doi: 10.1002/pbc.21214. Pediatr Blood Cancer. 2008. PMID: 17420992

8

Initial testing of the VEGFR inhibitor AZD2171 by the pediatric preclinical testing program.

Maris JM, Courtright J, Houghton PJ, Morton CL, Gorlick R, Kolb EA, Lock R, Tajbakhsh M, Reynolds CP, Keir ST, Wu J, Smith MA. Maris JM, et al. Among authors: lock r. Pediatr Blood Cancer. 2008 Mar;50(3):581-7. doi: 10.1002/pbc.21232. Pediatr Blood Cancer. 2008. PMID: 17457854

9

Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia.

Bachmann PS, Gorman R, Papa RA, Bardell JE, Ford J, Kees UR, Marshall GM, Lock RB. Bachmann PS, et al. Among authors: lock rb. Cancer Res. 2007 May 1;67(9):4482-90. doi: 10.1158/0008-5472.CAN-06-4244. Cancer Res. 2007. PMID: 17483364

10

Activity of vincristine, L-ASP, and dexamethasone against acute lymphoblastic leukemia is enhanced by the BH3-mimetic ABT-737 in vitro and in vivo.

Kang MH, Kang YH, Szymanska B, Wilczynska-Kalak U, Sheard MA, Harned TM, Lock RB, Reynolds CP. Kang MH, et al. Blood. 2007 Sep 15;110(6):2057-66. doi: 10.1182/blood-2007-03-080325. Epub 2007 May 29. Blood. 2007. PMID: 17536015 Free article.

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