Hall MD - Search Results

1

Evidence for dual mode of action of a thiosemicarbazone, NSC73306: a potent substrate of the multidrug resistance linked ABCG2 transporter.

Wu CP, Shukla S, Calcagno AM, Hall MD, Gottesman MM, Ambudkar SV. Wu CP, et al. Among authors: hall md. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3287-96. doi: 10.1158/1535-7163.MCT-07-2005. Mol Cancer Ther. 2007. PMID: 18089722 Free PMC article.

2

The role of cellular accumulation in determining sensitivity to platinum-based chemotherapy.

Hall MD, Okabe M, Shen DW, Liang XJ, Gottesman MM. Hall MD, et al. Annu Rev Pharmacol Toxicol. 2008;48:495-535. doi: 10.1146/annurev.pharmtox.48.080907.180426. Annu Rev Pharmacol Toxicol. 2008. PMID: 17937596 Review.

3

Profiling SLCO and SLC22 genes in the NCI-60 cancer cell lines to identify drug uptake transporters.

Okabe M, Szakács G, Reimers MA, Suzuki T, Hall MD, Abe T, Weinstein JN, Gottesman MM. Okabe M, et al. Among authors: hall md. Mol Cancer Ther. 2008 Sep;7(9):3081-91. doi: 10.1158/1535-7163.MCT-08-0539. Mol Cancer Ther. 2008. PMID: 18790787 Free PMC article.

4

Synthesis, activity, and pharmacophore development for isatin-beta-thiosemicarbazones with selective activity toward multidrug-resistant cells.

Hall MD, Salam NK, Hellawell JL, Fales HM, Kensler CB, Ludwig JA, Szakács G, Hibbs DE, Gottesman MM. Hall MD, et al. J Med Chem. 2009 May 28;52(10):3191-204. doi: 10.1021/jm800861c. J Med Chem. 2009. PMID: 19397322 Free PMC article.

5

A dual-fluorescence high-throughput cell line system for probing multidrug resistance.

Brimacombe KR, Hall MD, Auld DS, Inglese J, Austin CP, Gottesman MM, Fung KL. Brimacombe KR, et al. Among authors: hall md. Assay Drug Dev Technol. 2009 Jun;7(3):233-49. doi: 10.1089/adt.2008.165. Assay Drug Dev Technol. 2009. PMID: 19548831 Free PMC article.

6

Imaging the function of P-glycoprotein with radiotracers: pharmacokinetics and in vivo applications.

Kannan P, John C, Zoghbi SS, Halldin C, Gottesman MM, Innis RB, Hall MD. Kannan P, et al. Among authors: hall md. Clin Pharmacol Ther. 2009 Oct;86(4):368-77. doi: 10.1038/clpt.2009.138. Epub 2009 Jul 22. Clin Pharmacol Ther. 2009. PMID: 19625998 Free PMC article. Review.

7

Is resistance useless? Multidrug resistance and collateral sensitivity.

Hall MD, Handley MD, Gottesman MM. Hall MD, et al. Trends Pharmacol Sci. 2009 Oct;30(10):546-56. doi: 10.1016/j.tips.2009.07.003. Epub 2009 Sep 15. Trends Pharmacol Sci. 2009. PMID: 19762091 Free PMC article. Review.

8

Identification of compounds selectively killing multidrug-resistant cancer cells.

Türk D, Hall MD, Chu BF, Ludwig JA, Fales HM, Gottesman MM, Szakács G. Türk D, et al. Among authors: hall md. Cancer Res. 2009 Nov 1;69(21):8293-301. doi: 10.1158/0008-5472.CAN-09-2422. Epub 2009 Oct 20. Cancer Res. 2009. PMID: 19843850 Free PMC article.

9

N-desmethyl-loperamide is selective for P-glycoprotein among three ATP-binding cassette transporters at the blood-brain barrier.

Kannan P, Brimacombe KR, Zoghbi SS, Liow JS, Morse C, Taku AK, Pike VW, Halldin C, Innis RB, Gottesman MM, Hall MD. Kannan P, et al. Among authors: hall md. Drug Metab Dispos. 2010 Jun;38(6):917-22. doi: 10.1124/dmd.109.031161. Epub 2010 Mar 8. Drug Metab Dispos. 2010. PMID: 20212014 Free PMC article.

10

Lysosomal trapping of a radiolabeled substrate of P-glycoprotein as a mechanism for signal amplification in PET.

Kannan P, Brimacombe KR, Kreisl WC, Liow JS, Zoghbi SS, Telu S, Zhang Y, Pike VW, Halldin C, Gottesman MM, Innis RB, Hall MD. Kannan P, et al. Among authors: hall md. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2593-8. doi: 10.1073/pnas.1014641108. Epub 2011 Jan 24. Proc Natl Acad Sci U S A. 2011. PMID: 21262843 Free PMC article.

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