Wittmann S - Search Results

1

The mTOR inhibitor everolimus induces proteinuria and renal deterioration in the remnant kidney model in the rat.

Vogelbacher R, Wittmann S, Braun A, Daniel C, Hugo C. Vogelbacher R, et al. Among authors: wittmann s. Transplantation. 2007 Dec 15;84(11):1492-9. doi: 10.1097/01.tp.0000282866.92367.99. Transplantation. 2007. PMID: 18091526

2

The mTOR inhibitor everolimus attenuates the time course of chronic anti-Thy1 nephritis in the rat.

Wittmann S, Daniel C, Braun A, Vogelbacher R, Shimizu F, Kawachi H, Hugo C. Wittmann S, et al. Nephron Exp Nephrol. 2008;108(2):e45-56. doi: 10.1159/000116112. Epub 2008 Feb 13. Nephron Exp Nephrol. 2008. PMID: 18270495

3

PDE-5 inhibition impedes TSP-1 expression, TGF-beta activation and matrix accumulation in experimental glomerulonephritis.

Hohenstein B, Daniel C, Wittmann S, Hugo C. Hohenstein B, et al. Among authors: wittmann s. Nephrol Dial Transplant. 2008 Nov;23(11):3427-36. doi: 10.1093/ndt/gfn319. Epub 2008 Jul 2. Nephrol Dial Transplant. 2008. PMID: 18596129

4

Long-term treatment of sirolimus but not cyclosporine ameliorates diabetic nephropathy in the rat.

Wittmann S, Daniel C, Stief A, Vogelbacher R, Amann K, Hugo C. Wittmann S, et al. Transplantation. 2009 May 15;87(9):1290-9. doi: 10.1097/TP.0b013e3181a192bd. Transplantation. 2009. PMID: 19424027

5

Bortezomib and sirolimus inhibit the chronic active antibody-mediated rejection in experimental renal transplantation in the rat.

Vogelbacher R, Meister S, Gückel E, Starke C, Wittmann S, Stief A, Voll R, Daniel C, Hugo C. Vogelbacher R, et al. Among authors: wittmann s. Nephrol Dial Transplant. 2010 Nov;25(11):3764-73. doi: 10.1093/ndt/gfq230. Epub 2010 Apr 28. Nephrol Dial Transplant. 2010. PMID: 20466656

6

Design, Synthesis and Cellular Characterization of a Dual Inhibitor of 5-Lipoxygenase and Soluble Epoxide Hydrolase.

Meirer K, Glatzel D, Kretschmer S, Wittmann SK, Hartmann M, Blöcher R, Angioni C, Geisslinger G, Steinhilber D, Hofmann B, Fürst R, Proschak E. Meirer K, et al. Among authors: wittmann sk. Molecules. 2016 Dec 29;22(1):45. doi: 10.3390/molecules22010045. Molecules. 2016. PMID: 28036068 Free PMC article.

7

A Dual Modulator of Farnesoid X Receptor and Soluble Epoxide Hydrolase To Counter Nonalcoholic Steatohepatitis.

Schmidt J, Rotter M, Weiser T, Wittmann S, Weizel L, Kaiser A, Heering J, Goebel T, Angioni C, Wurglics M, Paulke A, Geisslinger G, Kahnt A, Steinhilber D, Proschak E, Merk D. Schmidt J, et al. Among authors: wittmann s. J Med Chem. 2017 Sep 28;60(18):7703-7724. doi: 10.1021/acs.jmedchem.7b00398. Epub 2017 Sep 8. J Med Chem. 2017. PMID: 28845983

8

Synthesis and structure-activity relationship studies of novel dual inhibitors of soluble epoxide hydrolase and 5-lipoxygenase.

Meirer K, Rödl CB, Wisniewska JM, George S, Häfner AK, Buscató EL, Klingler FM, Hahn S, Berressem D, Wittmann SK, Steinhilber D, Hofmann B, Proschak E. Meirer K, et al. Among authors: wittmann sk. J Med Chem. 2013 Feb 28;56(4):1777-81. doi: 10.1021/jm301617j. Epub 2013 Feb 7. J Med Chem. 2013. PMID: 23356879

9

N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ Modulators.

Blöcher R, Lamers C, Wittmann SK, Merk D, Hartmann M, Weizel L, Diehl O, Brüggerhoff A, Boß M, Kaiser A, Schader T, Göbel T, Grundmann M, Angioni C, Heering J, Geisslinger G, Wurglics M, Kostenis E, Brüne B, Steinhilber D, Schubert-Zsilavecz M, Kahnt AS, Proschak E. Blöcher R, et al. Among authors: wittmann sk. J Med Chem. 2016 Jan 14;59(1):61-81. doi: 10.1021/acs.jmedchem.5b01239. Epub 2015 Dec 25. J Med Chem. 2016. PMID: 26595749

10

Design, Synthesis, and Structure-Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase.

Hiesinger K, Kramer JS, Beyer S, Eckes T, Brunst S, Flauaus C, Wittmann SK, Weizel L, Kaiser A, Kretschmer SBM, George S, Angioni C, Heering J, Geisslinger G, Schubert-Zsilavecz M, Schmidtko A, Pogoryelov D, Pfeilschifter J, Hofmann B, Steinhilber D, Schwalm S, Proschak E. Hiesinger K, et al. Among authors: wittmann sk. J Med Chem. 2020 Oct 22;63(20):11498-11521. doi: 10.1021/acs.jmedchem.0c00561. Epub 2020 Oct 12. J Med Chem. 2020. PMID: 33044073

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