O'Hagan DT - Search Results

1

Combination adjuvants for the induction of potent, long-lasting antibody and T-cell responses to influenza vaccine in mice.

Wack A, Baudner BC, Hilbert AK, Manini I, Nuti S, Tavarini S, Scheffczik H, Ugozzoli M, Singh M, Kazzaz J, Montomoli E, Del Giudice G, Rappuoli R, O'Hagan DT. Wack A, et al. Vaccine. 2008 Jan 24;26(4):552-61. doi: 10.1016/j.vaccine.2007.11.054. Epub 2007 Dec 7. Vaccine. 2008. PMID: 18162266

2

Cationic microparticles are a potent delivery system for a HCV DNA vaccine.

O'Hagan DT, Singh M, Dong C, Ugozzoli M, Berger K, Glazer E, Selby M, Wininger M, Ng P, Crawford K, Paliard X, Coates S, Houghton M. O'Hagan DT, et al. Vaccine. 2004 Dec 16;23(5):672-80. doi: 10.1016/j.vaccine.2004.06.037. Vaccine. 2004. PMID: 15542189

3

A preliminary evaluation of alternative adjuvants to alum using a range of established and new generation vaccine antigens.

Singh M, Ugozzoli M, Kazzaz J, Chesko J, Soenawan E, Mannucci D, Titta F, Contorni M, Volpini G, Del Guidice G, O'Hagan DT. Singh M, et al. Vaccine. 2006 Mar 6;24(10):1680-6. doi: 10.1016/j.vaccine.2005.09.046. Epub 2005 Oct 6. Vaccine. 2006. PMID: 16300864

4

MF59 emulsion is an effective delivery system for a synthetic TLR4 agonist (E6020).

Baudner BC, Ronconi V, Casini D, Tortoli M, Kazzaz J, Singh M, Hawkins LD, Wack A, O'Hagan DT. Baudner BC, et al. Pharm Res. 2009 Jun;26(6):1477-85. doi: 10.1007/s11095-009-9859-5. Epub 2009 Mar 3. Pharm Res. 2009. PMID: 19255727

5

Bioadhesive delivery systems for mucosal vaccine delivery.

Baudner BC, O'Hagan DT. Baudner BC, et al. J Drug Target. 2010 Dec;18(10):752-70. doi: 10.3109/1061186X.2010.529143. Epub 2010 Nov 2. J Drug Target. 2010. PMID: 21039314 Review.

6

Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes.

Calabro S, Tortoli M, Baudner BC, Pacitto A, Cortese M, O'Hagan DT, De Gregorio E, Seubert A, Wack A. Calabro S, et al. Vaccine. 2011 Feb 17;29(9):1812-23. doi: 10.1016/j.vaccine.2010.12.090. Epub 2011 Jan 6. Vaccine. 2011. PMID: 21215831

7

An alternative renewable source of squalene for use in emulsion adjuvants.

Brito LA, Chan M, Baudner B, Gallorini S, Santos G, O'Hagan DT, Singh M. Brito LA, et al. Vaccine. 2011 Aug 26;29(37):6262-8. doi: 10.1016/j.vaccine.2011.06.067. Epub 2011 Jun 30. Vaccine. 2011. PMID: 21723355

8

MF59 oil-in-water emulsion in combination with a synthetic TLR4 agonist (E6020) is a potent adjuvant for a combination Meningococcus vaccine.

Singh M, Kazzaz J, Ugozzoli M, Baudner B, Pizza M, Giuliani M, Hawkins LD, Otten G, O'Hagan DT. Singh M, et al. Hum Vaccin Immunother. 2012 Apr;8(4):486-90. doi: 10.4161/hv.19229. Hum Vaccin Immunother. 2012. PMID: 22832252 Free article.

9

The adjuvant effect of MF59 is due to the oil-in-water emulsion formulation, none of the individual components induce a comparable adjuvant effect.

Calabro S, Tritto E, Pezzotti A, Taccone M, Muzzi A, Bertholet S, De Gregorio E, O'Hagan DT, Baudner B, Seubert A. Calabro S, et al. Vaccine. 2013 Jul 18;31(33):3363-9. doi: 10.1016/j.vaccine.2013.05.007. Epub 2013 May 16. Vaccine. 2013. PMID: 23684834

10

Sublingual immunization with a subunit influenza vaccine elicits comparable systemic immune response as intramuscular immunization, but also induces local IgA and TH17 responses.

Gallorini S, Taccone M, Bonci A, Nardelli F, Casini D, Bonificio A, Kommareddy S, Bertholet S, O'Hagan DT, Baudner BC. Gallorini S, et al. Vaccine. 2014 Apr 25;32(20):2382-8. doi: 10.1016/j.vaccine.2013.12.043. Epub 2014 Jan 13. Vaccine. 2014. PMID: 24434044

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