Mols R - Search Results

1

Increasing the oral bioavailability of the poorly water soluble drug itraconazole with ordered mesoporous silica.

Mellaerts R, Mols R, Jammaer JA, Aerts CA, Annaert P, Van Humbeeck J, Van den Mooter G, Augustijns P, Martens JA. Mellaerts R, et al. Among authors: mols r. Eur J Pharm Biopharm. 2008 May;69(1):223-30. doi: 10.1016/j.ejpb.2007.11.006. Epub 2007 Nov 23. Eur J Pharm Biopharm. 2008. PMID: 18164930

2

Apricot extract inhibits the P-gp-mediated efflux of talinolol.

Deferme S, Mols R, Van Driessche W, Augustijns P. Deferme S, et al. Among authors: mols r. J Pharm Sci. 2002 Dec;91(12):2539-48. doi: 10.1002/jps.10262. J Pharm Sci. 2002. PMID: 12434397

3

Metabolism of stevioside in pigs and intestinal absorption characteristics of stevioside, rebaudioside A and steviol.

Geuns JM, Augustijns P, Mols R, Buyse JG, Driessen B. Geuns JM, et al. Among authors: mols r. Food Chem Toxicol. 2003 Nov;41(11):1599-607. doi: 10.1016/s0278-6915(03)00191-1. Food Chem Toxicol. 2003. PMID: 12963013

4

HPLC with programmed wavelength fluorescence detection for the simultaneous determination of marker compounds of integrity and P-gp functionality in the Caco-2 intestinal absorption model.

Augustijns P, Mols R. Augustijns P, et al. Among authors: mols r. J Pharm Biomed Anal. 2004 Mar 10;34(5):971-8. doi: 10.1016/j.jpba.2003.11.016. J Pharm Biomed Anal. 2004. PMID: 15019031

5

Human bioavailability of propranolol from a matrix-in-cylinder system with a HPMC-Gelucire core.

Mehuys E, Remon JP, Korst A, Van Bortel L, Mols R, Augustijns P, Porter C, Vervaet C. Mehuys E, et al. Among authors: mols r. J Control Release. 2005 Oct 20;107(3):523-36. doi: 10.1016/j.jconrel.2005.06.019. J Control Release. 2005. PMID: 16055224 Clinical Trial.

6

Sulfasalazine transport in in-vitro, ex-vivo and in-vivo absorption models: contribution of efflux carriers and their modulation by co-administration of synthetic nature-identical fruit extracts.

Mols R, Deferme S, Augustijns P. Mols R, et al. J Pharm Pharmacol. 2005 Dec;57(12):1565-73. doi: 10.1211/jpp.57.12.0006. J Pharm Pharmacol. 2005. PMID: 16354400

7

Multidrug resistance-associated protein 2 (MRP2) affects hepatobiliary elimination but not the intestinal disposition of tenofovir disoproxil fumarate and its metabolites.

Mallants R, Van Oosterwyck K, Van Vaeck L, Mols R, De Clercq E, Augustijns P. Mallants R, et al. Among authors: mols r. Xenobiotica. 2005 Oct-Nov;35(10-11):1055-66. doi: 10.1080/00498250500354493. Xenobiotica. 2005. PMID: 16393861

8

Ordered mesoporous silica induces pH-independent supersaturation of the basic low solubility compound itraconazole resulting in enhanced transepithelial transport.

Mellaerts R, Mols R, Kayaert P, Annaert P, Van Humbeeck J, Van den Mooter G, Martens JA, Augustijns P. Mellaerts R, et al. Among authors: mols r. Int J Pharm. 2008 Jun 5;357(1-2):169-79. doi: 10.1016/j.ijpharm.2008.01.049. Epub 2008 Feb 3. Int J Pharm. 2008. PMID: 18325700

9

Intestinal perfusion with mesenteric blood sampling in wild-type and knockout mice: evaluation of a novel tool in biopharmaceutical drug profiling.

Mols R, Brouwers J, Schinkel AH, Annaert P, Augustijns P. Mols R, et al. Drug Metab Dispos. 2009 Jun;37(6):1334-7. doi: 10.1124/dmd.109.026591. Epub 2009 Mar 9. Drug Metab Dispos. 2009. PMID: 19273528

10

Itraconazole/TPGS/Aerosil200 solid dispersions: characterization, physical stability and in vivo performance.

Van Eerdenbrugh B, Van Speybroeck M, Mols R, Houthoofd K, Martens JA, Froyen L, Van Humbeeck J, Augustijns P, Van den Mooter G. Van Eerdenbrugh B, et al. Among authors: mols r. Eur J Pharm Sci. 2009 Oct 8;38(3):270-8. doi: 10.1016/j.ejps.2009.08.002. Epub 2009 Aug 15. Eur J Pharm Sci. 2009. PMID: 19686846

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