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Page 1
Discovery of potent LPA2 (EDG4) antagonists as potential anticancer agents.
Beck HP, Kohn T, Rubenstein S, Hedberg C, Schwandner R, Hasslinger K, Dai K, Li C, Liang L, Wesche H, Frank B, An S, Wickramasinghe D, Jaen J, Medina J, Hungate R, Shen W. Beck HP, et al. Among authors: schwandner r. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1037-41. doi: 10.1016/j.bmcl.2007.12.024. Epub 2008 Jan 4. Bioorg Med Chem Lett. 2008. PMID: 18178086
Allosteric rescuing of loss-of-function FFAR2 mutations.
Swaminath G, Jaeckel P, Guo Q, Cardozo M, Weiszmann J, Lindberg R, Wang Y, Schwandner R, Li Y. Swaminath G, et al. Among authors: schwandner r. FEBS Lett. 2010 Oct 8;584(19):4208-14. doi: 10.1016/j.febslet.2010.09.007. Epub 2010 Sep 17. FEBS Lett. 2010. PMID: 20837008 Free article.
High throughput screening for orphan and liganded GPCRs.
Xiao SH, Reagan JD, Lee PH, Fu A, Schwandner R, Zhao X, Knop J, Beckmann H, Young SW. Xiao SH, et al. Among authors: schwandner r. Comb Chem High Throughput Screen. 2008 Mar;11(3):195-215. doi: 10.2174/138620708783877762. Comb Chem High Throughput Screen. 2008. PMID: 18336213 Review.
Activation of FFA1 mediates GLP-1 secretion in mice. Evidence for allosterism at FFA1.
Xiong Y, Swaminath G, Cao Q, Yang L, Guo Q, Salomonis H, Lu J, Houze JB, Dransfield PJ, Wang Y, Liu JJ, Wong S, Schwandner R, Steger F, Baribault H, Liu L, Coberly S, Miao L, Zhang J, Lin DC, Schwarz M. Xiong Y, et al. Among authors: schwandner r. Mol Cell Endocrinol. 2013 Apr 30;369(1-2):119-29. doi: 10.1016/j.mce.2013.01.009. Epub 2013 Feb 9. Mol Cell Endocrinol. 2013. PMID: 23403053
Mutational analysis of G-protein coupled receptor--FFA2.
Swaminath G, Jaeckel P, Guo Q, Cardozo M, Weiszmann J, Lindberg R, Wang Y, Schwandner R, Li Y. Swaminath G, et al. Among authors: schwandner r. Biochem Biophys Res Commun. 2011 Feb 4;405(1):122-7. doi: 10.1016/j.bbrc.2010.12.139. Epub 2011 Jan 7. Biochem Biophys Res Commun. 2011. PMID: 21216233
26 results