Lian L - Search Results

1

Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.

Wang Y, Litvinov RI, Chen X, Bach TL, Lian L, Petrich BG, Monkley SJ, Kanaho Y, Critchley DR, Sasaki T, Birnbaum MJ, Weisel JW, Hartwig J, Abrams CS. Wang Y, et al. Among authors: lian l. J Clin Invest. 2008 Feb;118(2):812-9. doi: 10.1172/JCI34239. J Clin Invest. 2008. PMID: 18188447 Free PMC article.

2

PIP5KI gamma is required for cardiovascular and neuronal development.

Wang Y, Lian L, Golden JA, Morrisey EE, Abrams CS. Wang Y, et al. Among authors: lian l. Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11748-53. doi: 10.1073/pnas.0700019104. Epub 2007 Jul 3. Proc Natl Acad Sci U S A. 2007. PMID: 17609388 Free PMC article.

3

Loss of PIP5KIbeta demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation.

Wang Y, Chen X, Lian L, Tang T, Stalker TJ, Sasaki T, Kanaho Y, Brass LF, Choi JK, Hartwig JH, Abrams CS. Wang Y, et al. Among authors: lian l. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):14064-9. doi: 10.1073/pnas.0804139105. Epub 2008 Sep 4. Proc Natl Acad Sci U S A. 2008. PMID: 18772378 Free PMC article.

4

Platelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion.

Wang Y, Zhao L, Suzuki A, Lian L, Min SH, Wang Z, Litvinov RI, Stalker TJ, Yago T, Klopocki AG, Schmidtke DW, Yin H, Choi JK, McEver RP, Weisel JW, Hartwig JH, Abrams CS. Wang Y, et al. Among authors: lian l. Blood. 2013 Apr 4;121(14):2743-52. doi: 10.1182/blood-2012-07-445205. Epub 2013 Jan 31. Blood. 2013. PMID: 23372168 Free PMC article.

5

Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis.

Lian L, Wang Y, Flick M, Choi J, Scott EW, Degen J, Lemmon MA, Abrams CS. Lian L, et al. Blood. 2009 Apr 9;113(15):3577-84. doi: 10.1182/blood-2008-09-178913. Epub 2009 Feb 3. Blood. 2009. PMID: 19190246 Free PMC article.

6

The relative role of PLCbeta and PI3Kgamma in platelet activation.

Lian L, Wang Y, Draznin J, Eslin D, Bennett JS, Poncz M, Wu D, Abrams CS. Lian L, et al. Blood. 2005 Jul 1;106(1):110-7. doi: 10.1182/blood-2004-05-2005. Epub 2005 Feb 10. Blood. 2005. PMID: 15705797 Free PMC article.

7

Phospholipase cbeta is critical for T cell chemotaxis.

Bach TL, Chen QM, Kerr WT, Wang Y, Lian L, Choi JK, Wu D, Kazanietz MG, Koretzky GA, Zigmond S, Abrams CS. Bach TL, et al. Among authors: lian l. J Immunol. 2007 Aug 15;179(4):2223-7. doi: 10.4049/jimmunol.179.4.2223. J Immunol. 2007. PMID: 17675482 Free PMC article.

8

RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation.

Suzuki A, Shin JW, Wang Y, Min SH, Poncz M, Choi JK, Discher DE, Carpenter CL, Lian L, Zhao L, Wang Y, Abrams CS. Suzuki A, et al. Among authors: lian l. PLoS One. 2013 Jul 23;8(7):e69315. doi: 10.1371/journal.pone.0069315. Print 2013. PLoS One. 2013. PMID: 23935982 Free PMC article.

9

Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo.

Bezman NA, Lian L, Abrams CS, Brass LF, Kahn ML, Jordan MS, Koretzky GA. Bezman NA, et al. Among authors: lian l. J Exp Med. 2008 Aug 4;205(8):1775-88. doi: 10.1084/jem.20080240. Epub 2008 Jul 28. J Exp Med. 2008. PMID: 18663126 Free PMC article.

10

Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice.

Min SH, Suzuki A, Stalker TJ, Zhao L, Wang Y, McKennan C, Riese MJ, Guzman JF, Zhang S, Lian L, Joshi R, Meng R, Seeholzer SH, Choi JK, Koretzky G, Marks MS, Abrams CS. Min SH, et al. Among authors: lian l. Nat Commun. 2014 Sep 2;5:4691. doi: 10.1038/ncomms5691. Nat Commun. 2014. PMID: 25178411 Free PMC article.

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