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Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?
Le Hellard S, Theisen FM, Haberhausen M, Raeder MB, Fernø J, Gebhardt S, Hinney A, Remschmidt H, Krieg JC, Mehler-Wex C, Nöthen MM, Hebebrand J, Steen VM. Le Hellard S, et al. Mol Psychiatry. 2009 Mar;14(3):308-17. doi: 10.1038/sj.mp.4002133. Epub 2008 Jan 15. Mol Psychiatry. 2009. PMID: 18195716
Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples.
Le Hellard S, Mühleisen TW, Djurovic S, Fernø J, Ouriaghi Z, Mattheisen M, Vasilescu C, Raeder MB, Hansen T, Strohmaier J, Georgi A, Brockschmidt FF, Melle I, Nenadic I, Sauer H, Rietschel M, Nöthen MM, Werge T, Andreassen OA, Cichon S, Steen VM. Le Hellard S, et al. Mol Psychiatry. 2010 May;15(5):463-72. doi: 10.1038/mp.2008.110. Epub 2008 Oct 21. Mol Psychiatry. 2010. PMID: 18936756
Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are associated with memory and general cognitive abilities.
Le Hellard S, Håvik B, Espeseth T, Breilid H, Løvlie R, Luciano M, Gow AJ, Harris SE, Starr JM, Wibrand K, Lundervold AJ, Porteous DJ, Bramham CR, Deary IJ, Reinvang I, Steen VM. Le Hellard S, et al. PLoS One. 2009 Oct 21;4(10):e7534. doi: 10.1371/journal.pone.0007534. PLoS One. 2009. PMID: 19844571 Free PMC article.
Lipogenic effects of psychotropic drugs: focus on the SREBP system.
Ferno J, Skrede S, Vik-Mo AO, Jassim G, Le Hellard S, Steen VM. Ferno J, et al. Among authors: le hellard s. Front Biosci (Landmark Ed). 2011 Jan 1;16(1):49-60. doi: 10.2741/3675. Front Biosci (Landmark Ed). 2011. PMID: 21196158 Free article. Review.
The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia.
Håvik B, Le Hellard S, Rietschel M, Lybæk H, Djurovic S, Mattheisen M, Mühleisen TW, Degenhardt F, Priebe L, Maier W, Breuer R, Schulze TG, Agartz I, Melle I, Hansen T, Bramham CR, Nöthen MM, Stevens B, Werge T, Andreassen OA, Cichon S, Steen VM. Håvik B, et al. Among authors: le hellard s. Biol Psychiatry. 2011 Jul 1;70(1):35-42. doi: 10.1016/j.biopsych.2011.01.030. Epub 2011 Mar 24. Biol Psychiatry. 2011. PMID: 21439553
111 results