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CTLA-4 directly inhibits osteoclast formation.
Axmann R, Herman S, Zaiss M, Franz S, Polzer K, Zwerina J, Herrmann M, Smolen J, Schett G. Axmann R, et al. Among authors: smolen j. Ann Rheum Dis. 2008 Nov;67(11):1603-9. doi: 10.1136/ard.2007.080713. Epub 2008 Jan 18. Ann Rheum Dis. 2008. PMID: 18203760
Enhanced expression of heat shock protein 70 (hsp70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue. Differential regulation of hsp70 expression and hsf1 activation in synovial fibroblasts by proinflammatory cytokines, shear stress, and antiinflammatory drugs.
Schett G, Redlich K, Xu Q, Bizan P, Gröger M, Tohidast-Akrad M, Kiener H, Smolen J, Steiner G. Schett G, et al. Among authors: smolen j. J Clin Invest. 1998 Jul 15;102(2):302-11. doi: 10.1172/JCI2465. J Clin Invest. 1998. PMID: 9664071 Free PMC article.
The stressed synovium.
Schett G, Tohidast-Akrad M, Steiner G, Smolen J. Schett G, et al. Among authors: smolen j. Arthritis Res. 2001;3(2):80-6. doi: 10.1186/ar144. Epub 2001 Jan 9. Arthritis Res. 2001. PMID: 11178114 Free PMC article. Review.
Overexpression of transcription factor Ets-1 in rheumatoid arthritis synovial membrane: regulation of expression and activation by interleukin-1 and tumor necrosis factor alpha.
Redlich K, Kiener HP, Schett G, Tohidast-Akrad M, Selzer E, Radda I, Stummvoll GH, Steiner CW, Gröger M, Bitzan P, Zenz P, Smolen JS, Steiner G. Redlich K, et al. Among authors: smolen js. Arthritis Rheum. 2001 Feb;44(2):266-74. doi: 10.1002/1529-0131(200102)44:2<266::AID-ANR43>3.0.CO;2-G. Arthritis Rheum. 2001. PMID: 11229456 Free article.
Adenovirus-based overexpression of tissue inhibitor of metalloproteinases 1 reduces tissue damage in the joints of tumor necrosis factor alpha transgenic mice.
Schett G, Hayer S, Tohidast-Akrad M, Schmid BJ, Lang S, Türk B, Kainberger F, Haralambous S, Kollias G, Newby AC, Xu Q, Steiner G, Smolen J. Schett G, et al. Among authors: smolen j. Arthritis Rheum. 2001 Dec;44(12):2888-98. doi: 10.1002/1529-0131(200112)44:12<2888::aid-art477>3.0.co;2-3. Arthritis Rheum. 2001. PMID: 11762950 Free article.
1,158 results