Martinez ED - Search Results

1

A quantitative high-throughput screen identifies potential epigenetic modulators of gene expression.

Johnson RL, Huang W, Jadhav A, Austin CP, Inglese J, Martinez ED. Johnson RL, et al. Among authors: martinez ed. Anal Biochem. 2008 Apr 15;375(2):237-48. doi: 10.1016/j.ab.2007.12.028. Epub 2007 Dec 25. Anal Biochem. 2008. PMID: 18211814 Free PMC article.

2

Fluorescent protein-based cellular assays analyzed by laser-scanning microplate cytometry in 1536-well plate format.

Auld DS, Johnson RL, Zhang YQ, Veith H, Jadhav A, Yasgar A, Simeonov A, Zheng W, Martinez ED, Westwick JK, Austin CP, Inglese J. Auld DS, et al. Among authors: martinez ed. Methods Enzymol. 2006;414:566-89. doi: 10.1016/S0076-6879(06)14029-X. Methods Enzymol. 2006. PMID: 17110211

3

Identification of small molecule modulators of gene transcription with anticancer activity.

Tran TA, Wichterman-Kouznetsova J, Varghese D, Huang R, Huang W, Becker M, Austin CP, Inglese J, Johnson RL, Martinez ED. Tran TA, et al. Among authors: martinez ed. ACS Chem Biol. 2014 Nov 21;9(11):2603-11. doi: 10.1021/cb500532x. Epub 2014 Sep 16. ACS Chem Biol. 2014. PMID: 25188650 Free PMC article.

4

KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes.

Duan L, Rai G, Roggero C, Zhang QJ, Wei Q, Ma SH, Zhou Y, Santoyo J, Martinez ED, Xiao G, Raj GV, Jadhav A, Simeonov A, Maloney DJ, Rizo J, Hsieh JT, Liu ZP. Duan L, et al. Among authors: martinez ed. Chem Biol. 2015 Sep 17;22(9):1185-96. doi: 10.1016/j.chembiol.2015.08.007. Epub 2015 Sep 10. Chem Biol. 2015. PMID: 26364928 Free PMC article.

5

High-content fluorescence-based screening for epigenetic modulators.

Martinez ED, Dull AB, Beutler JA, Hager GL. Martinez ED, et al. Methods Enzymol. 2006;414:21-36. doi: 10.1016/S0076-6879(06)14002-1. Methods Enzymol. 2006. PMID: 17110184

6

Development of assays for nuclear receptor modulators using fluorescently tagged proteins.

Martinez ED, Hager GL. Martinez ED, et al. Methods Enzymol. 2006;414:37-50. doi: 10.1016/S0076-6879(06)14003-3. Methods Enzymol. 2006. PMID: 17110185

7

An estrogen receptor chimera senses ligands by nuclear translocation.

Martinez ED, Rayasam GV, Dull AB, Walker DA, Hager GL. Martinez ED, et al. J Steroid Biochem Mol Biol. 2005 Dec;97(4):307-21. doi: 10.1016/j.jsbmb.2005.06.033. Epub 2005 Sep 12. J Steroid Biochem Mol Biol. 2005. PMID: 16162406

8

Identification of four potential epigenetic modulators from the NCI structural diversity library using a cell-based assay.

Best AM, Chang J, Dull AB, Beutler JA, Martinez ED. Best AM, et al. Among authors: martinez ed. J Biomed Biotechnol. 2011;2011:868095. doi: 10.1155/2011/868095. Epub 2010 Dec 22. J Biomed Biotechnol. 2011. PMID: 21234371 Free PMC article.

9

Expression profiling of nuclear receptors in the NCI60 cancer cell panel reveals receptor-drug and receptor-gene interactions.

Holbeck S, Chang J, Best AM, Bookout AL, Mangelsdorf DJ, Martinez ED. Holbeck S, et al. Among authors: martinez ed. Mol Endocrinol. 2010 Jun;24(6):1287-96. doi: 10.1210/me.2010-0040. Epub 2010 Apr 7. Mol Endocrinol. 2010. PMID: 20375240 Free PMC article.

10

Successful strategies in the discovery of small-molecule epigenetic modulators with anticancer potential.

Bayo J, Dalvi MP, Martinez ED. Bayo J, et al. Among authors: martinez ed. Future Med Chem. 2015;7(16):2243-61. doi: 10.4155/fmc.15.140. Epub 2015 Oct 29. Future Med Chem. 2015. PMID: 26510529 Review.

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