Debiec-Rychter M - Search Results

1

Clinical implications of mutational analysis in gastrointestinal stromal tumours.

Hoeben A, Schöffski P, Debiec-Rychter M. Hoeben A, et al. Br J Cancer. 2008 Feb 26;98(4):684-8. doi: 10.1038/sj.bjc.6604217. Epub 2008 Feb 5. Br J Cancer. 2008. PMID: 18253129 Free PMC article. Review.

2

High efficacy of panobinostat towards human gastrointestinal stromal tumors in a xenograft mouse model.

Floris G, Debiec-Rychter M, Sciot R, Stefan C, Fieuws S, Machiels K, Atadja P, Wozniak A, Faa G, Schöffski P. Floris G, et al. Clin Cancer Res. 2009 Jun 15;15(12):4066-76. doi: 10.1158/1078-0432.CCR-08-2588. Epub 2009 Jun 9. Clin Cancer Res. 2009. PMID: 19509176

3

Implications of mutational analysis for the management of patients with gastrointestinal stromal tumors and the application of targeted therapies.

Wozniak A, Floris G, Debiec-Rychter M, Sciot R, Schöffski P. Wozniak A, et al. Cancer Invest. 2010 Oct;28(8):839-48. doi: 10.3109/07357907.2010.494322. Cancer Invest. 2010. PMID: 20690803 Review.

4

The heat shock protein 90 inhibitor IPI-504 induces KIT degradation, tumor shrinkage, and cell proliferation arrest in xenograft models of gastrointestinal stromal tumors.

Floris G, Debiec-Rychter M, Wozniak A, Stefan C, Normant E, Faa G, Machiels K, Vanleeuw U, Sciot R, Schöffski P. Floris G, et al. Mol Cancer Ther. 2011 Oct;10(10):1897-908. doi: 10.1158/1535-7163.MCT-11-0148. Epub 2011 Aug 8. Mol Cancer Ther. 2011. PMID: 21825009

5

A potent combination of the novel PI3K Inhibitor, GDC-0941, with imatinib in gastrointestinal stromal tumor xenografts: long-lasting responses after treatment withdrawal.

Floris G, Wozniak A, Sciot R, Li H, Friedman L, Van Looy T, Wellens J, Vermaelen P, Deroose CM, Fletcher JA, Debiec-Rychter M, Schöffski P. Floris G, et al. Clin Cancer Res. 2013 Feb 1;19(3):620-30. doi: 10.1158/1078-0432.CCR-12-2853. Epub 2012 Dec 11. Clin Cancer Res. 2013. PMID: 23231951 Free PMC article.

6

Unbiased compound screening identifies unexpected drug sensitivities and novel treatment options for gastrointestinal stromal tumors.

Boichuk S, Lee DJ, Mehalek KR, Makielski KR, Wozniak A, Seneviratne DS, Korzeniewski N, Cuevas R, Parry JA, Brown MF, Zewe J, Taguchi T, Kuan SF, Schöffski P, Debiec-Rychter M, Duensing A. Boichuk S, et al. Cancer Res. 2014 Feb 15;74(4):1200-13. doi: 10.1158/0008-5472.CAN-13-1955. Epub 2014 Jan 2. Cancer Res. 2014. PMID: 24385214

7

Tumor genotype is an independent prognostic factor in primary gastrointestinal stromal tumors of gastric origin: a european multicenter analysis based on ConticaGIST.

Wozniak A, Rutkowski P, Schöffski P, Ray-Coquard I, Hostein I, Schildhaus HU, Le Cesne A, Bylina E, Limon J, Blay JY, Siedlecki JA, Wardelmann E, Sciot R, Coindre JM, Debiec-Rychter M. Wozniak A, et al. Clin Cancer Res. 2014 Dec 1;20(23):6105-16. doi: 10.1158/1078-0432.CCR-14-1677. Epub 2014 Oct 7. Clin Cancer Res. 2014. PMID: 25294914

8

Phosphoinositide 3-kinase inhibitors combined with imatinib in patient-derived xenograft models of gastrointestinal stromal tumors: rationale and efficacy.

Van Looy T, Wozniak A, Floris G, Sciot R, Li H, Wellens J, Vanleeuw U, Fletcher JA, Manley PW, Debiec-Rychter M, Schöffski P. Van Looy T, et al. Clin Cancer Res. 2014 Dec 1;20(23):6071-82. doi: 10.1158/1078-0432.CCR-14-1823. Epub 2014 Oct 14. Clin Cancer Res. 2014. PMID: 25316817

9

Cabozantinib Is Active against Human Gastrointestinal Stromal Tumor Xenografts Carrying Different KIT Mutations.

Gebreyohannes YK, Schöffski P, Van Looy T, Wellens J, Vreys L, Cornillie J, Vanleeuw U, Aftab DT, Debiec-Rychter M, Sciot R, Wozniak A. Gebreyohannes YK, et al. Mol Cancer Ther. 2016 Dec;15(12):2845-2852. doi: 10.1158/1535-7163.MCT-16-0224. Epub 2016 Oct 24. Mol Cancer Ther. 2016. PMID: 27777285

10

Overcoming Cost Implications of Mutational Analysis in Patients with Gastrointestinal Stromal Tumors: A Pragmatic Approach.

Schöffski P, Wozniak A, Schöffski O, van Eycken L, Debiec-Rychter M. Schöffski P, et al. Oncol Res Treat. 2016;39(12):811-816. doi: 10.1159/000453057. Epub 2016 Nov 18. Oncol Res Treat. 2016. PMID: 27889785 Free article.

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