Steinman RM - Search Results

1

The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine.

Trumpfheller C, Caskey M, Nchinda G, Longhi MP, Mizenina O, Huang Y, Schlesinger SJ, Colonna M, Steinman RM. Trumpfheller C, et al. Among authors: steinman rm. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2574-9. doi: 10.1073/pnas.0711976105. Epub 2008 Feb 6. Proc Natl Acad Sci U S A. 2008. PMID: 18256187 Free PMC article.

2

Dendritic cell-targeted protein vaccines: a novel approach to induce T-cell immunity.

Trumpfheller C, Longhi MP, Caskey M, Idoyaga J, Bozzacco L, Keler T, Schlesinger SJ, Steinman RM. Trumpfheller C, et al. Among authors: steinman rm. J Intern Med. 2012 Feb;271(2):183-92. doi: 10.1111/j.1365-2796.2011.02496.x. Epub 2012 Jan 4. J Intern Med. 2012. PMID: 22126373 Free PMC article. Review.

3

HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation.

Granelli-Piperno A, Golebiowska A, Trumpfheller C, Siegal FP, Steinman RM. Granelli-Piperno A, et al. Among authors: steinman rm. Proc Natl Acad Sci U S A. 2004 May 18;101(20):7669-74. doi: 10.1073/pnas.0402431101. Epub 2004 May 5. Proc Natl Acad Sci U S A. 2004. PMID: 15128934 Free PMC article.

4

Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine.

Trumpfheller C, Finke JS, López CB, Moran TM, Moltedo B, Soares H, Huang Y, Schlesinger SJ, Park CG, Nussenzweig MC, Granelli-Piperno A, Steinman RM. Trumpfheller C, et al. Among authors: steinman rm. J Exp Med. 2006 Mar 20;203(3):607-17. doi: 10.1084/jem.20052005. Epub 2006 Feb 27. J Exp Med. 2006. PMID: 16505141 Free PMC article.

5

DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes.

Bozzacco L, Trumpfheller C, Siegal FP, Mehandru S, Markowitz M, Carrington M, Nussenzweig MC, Piperno AG, Steinman RM. Bozzacco L, et al. Among authors: steinman rm. Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1289-94. doi: 10.1073/pnas.0610383104. Epub 2007 Jan 17. Proc Natl Acad Sci U S A. 2007. PMID: 17229838 Free PMC article.

6

The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells.

Nchinda G, Kuroiwa J, Oks M, Trumpfheller C, Park CG, Huang Y, Hannaman D, Schlesinger SJ, Mizenina O, Nussenzweig MC, Uberla K, Steinman RM. Nchinda G, et al. Among authors: steinman rm. J Clin Invest. 2008 Apr;118(4):1427-36. doi: 10.1172/JCI34224. J Clin Invest. 2008. PMID: 18324335 Free PMC article.

7

Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant.

Longhi MP, Trumpfheller C, Idoyaga J, Caskey M, Matos I, Kluger C, Salazar AM, Colonna M, Steinman RM. Longhi MP, et al. Among authors: steinman rm. J Exp Med. 2009 Jul 6;206(7):1589-602. doi: 10.1084/jem.20090247. Epub 2009 Jun 29. J Exp Med. 2009. PMID: 19564349 Free PMC article.

8

HIV gag protein is efficiently cross-presented when targeted with an antibody towards the DEC-205 receptor in Flt3 ligand-mobilized murine DC.

Bozzacco L, Trumpfheller C, Huang Y, Longhi MP, Shimeliovich I, Schauer JD, Park CG, Steinman RM. Bozzacco L, et al. Among authors: steinman rm. Eur J Immunol. 2010 Jan;40(1):36-46. doi: 10.1002/eji.200939748. Eur J Immunol. 2010. PMID: 19830741 Free PMC article.

9

Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8+ T cells.

Nchinda G, Amadu D, Trumpfheller C, Mizenina O, Uberla K, Steinman RM. Nchinda G, et al. Among authors: steinman rm. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4281-6. doi: 10.1073/pnas.1000621107. Epub 2010 Feb 16. Proc Natl Acad Sci U S A. 2010. PMID: 20160099 Free PMC article.

10

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.

Idoyaga J, Lubkin A, Fiorese C, Lahoud MH, Caminschi I, Huang Y, Rodriguez A, Clausen BE, Park CG, Trumpfheller C, Steinman RM. Idoyaga J, et al. Among authors: steinman rm. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2384-9. doi: 10.1073/pnas.1019547108. Epub 2011 Jan 24. Proc Natl Acad Sci U S A. 2011. PMID: 21262813 Free PMC article.

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