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Genetic variation at the PCSK9 locus moderately lowers low-density lipoprotein cholesterol levels, but does not significantly lower vascular disease risk in an elderly population.
Polisecki E, Peter I, Robertson M, McMahon AD, Ford I, Packard C, Shepherd J, Jukema JW, Blauw GJ, Westendorp RG, de Craen AJ, Trompet S, Buckley BM, Murphy MB, Ordovas JM, Schaefer EJ; PROSPER Study Group. Polisecki E, et al. Among authors: schaefer ej. Atherosclerosis. 2008 Sep;200(1):95-101. doi: 10.1016/j.atherosclerosis.2007.12.005. Epub 2008 Feb 8. Atherosclerosis. 2008. PMID: 18262190 Free PMC article. Clinical Trial.
Low density lipoprotein particle size and coronary artery disease.
Campos H, Genest JJ Jr, Blijlevens E, McNamara JR, Jenner JL, Ordovas JM, Wilson PW, Schaefer EJ. Campos H, et al. Among authors: schaefer ej. Arterioscler Thromb. 1992 Feb;12(2):187-95. doi: 10.1161/01.atv.12.2.187. Arterioscler Thromb. 1992. PMID: 1543692
598 results