Lundquist S - Search Results

1

An in vitro blood-brain barrier model for high throughput (HTS) toxicological screening.

Culot M, Lundquist S, Vanuxeem D, Nion S, Landry C, Delplace Y, Dehouck MP, Berezowski V, Fenart L, Cecchelli R. Culot M, et al. Among authors: lundquist s. Toxicol In Vitro. 2008 Apr;22(3):799-811. doi: 10.1016/j.tiv.2007.12.016. Epub 2008 Jan 8. Toxicol In Vitro. 2008. PMID: 18280105

2

In vitro blood-brain barrier permeability and cerebral endothelial cell uptake of the neuroprotective nitrone compound NXY-059 in normoxic, hypoxic and ischemic conditions.

Dehouck MP, Cecchelli R, Richard Green A, Renftel M, Lundquist S. Dehouck MP, et al. Among authors: lundquist s. Brain Res. 2002 Nov 15;955(1-2):229-35. doi: 10.1016/s0006-8993(02)03469-8. Brain Res. 2002. PMID: 12419541

3

Modelling of the blood-brain barrier in drug discovery and development.

Cecchelli R, Berezowski V, Lundquist S, Culot M, Renftel M, Dehouck MP, Fenart L. Cecchelli R, et al. Among authors: lundquist s. Nat Rev Drug Discov. 2007 Aug;6(8):650-61. doi: 10.1038/nrd2368. Nat Rev Drug Discov. 2007. PMID: 17667956 Review.

4

A simple method for assessing free brain/free plasma ratios using an in vitro model of the blood brain barrier.

Culot M, Fabulas-da Costa A, Sevin E, Szorath E, Martinsson S, Renftel M, Hongmei Y, Cecchelli R, Lundquist S. Culot M, et al. Among authors: lundquist s. PLoS One. 2013 Dec 3;8(12):e80634. doi: 10.1371/journal.pone.0080634. eCollection 2013. PLoS One. 2013. PMID: 24312489 Free PMC article.

5

Transport screening of drug cocktails through an in vitro blood-brain barrier: is it a good strategy for increasing the throughput of the discovery pipeline?

Berezowski V, Landry C, Lundquist S, Dehouck L, Cecchelli R, Dehouck MP, Fenart L. Berezowski V, et al. Among authors: lundquist s. Pharm Res. 2004 May;21(5):756-60. doi: 10.1023/b:pham.0000026424.78528.11. Pharm Res. 2004. PMID: 15180330

6

Prediction of drug transport through the blood-brain barrier in vivo: a comparison between two in vitro cell models.

Lundquist S, Renftel M, Brillault J, Fenart L, Cecchelli R, Dehouck MP. Lundquist S, et al. Pharm Res. 2002 Jul;19(7):976-81. doi: 10.1023/a:1016462205267. Pharm Res. 2002. PMID: 12180550

7

Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: an in vitro study.

Culot M, Mysiorek C, Renftel M, Roussel BD, Hommet Y, Vivien D, Cecchelli R, Fenart L, Berezowski V, Dehouck MP, Lundquist S. Culot M, et al. Among authors: lundquist s. Brain Res. 2009 Oct 19;1294:144-52. doi: 10.1016/j.brainres.2009.07.035. Epub 2009 Jul 23. Brain Res. 2009. PMID: 19631615

8

Mimicking brain tissue binding in an in vitro model of the blood-brain barrier illustrates differences between in vitro and in vivo methods for assessing the rate of brain penetration.

Heymans M, Sevin E, Gosselet F, Lundquist S, Culot M. Heymans M, et al. Among authors: lundquist s. Eur J Pharm Biopharm. 2018 Jun;127:453-461. doi: 10.1016/j.ejpb.2018.03.007. Epub 2018 Mar 28. Eur J Pharm Biopharm. 2018. PMID: 29602020 Free article.

9

In vitro model for evaluating drug transport across the blood-brain barrier.

Cecchelli R, Dehouck B, Descamps L, Fenart L, Buée-Scherrer V V, Duhem C, Lundquist S, Rentfel M, Torpier G, Dehouck MP. Cecchelli R, et al. Among authors: lundquist s. Adv Drug Deliv Rev. 1999 Apr 5;36(2-3):165-178. doi: 10.1016/s0169-409x(98)00083-0. Adv Drug Deliv Rev. 1999. PMID: 10837714

10

Accelerated Caco-2 cell permeability model for drug discovery.

Sevin E, Dehouck L, Fabulas-da Costa A, Cecchelli R, Dehouck MP, Lundquist S, Culot M. Sevin E, et al. Among authors: lundquist s. J Pharmacol Toxicol Methods. 2013 Nov-Dec;68(3):334-9. doi: 10.1016/j.vascn.2013.07.004. Epub 2013 Aug 3. J Pharmacol Toxicol Methods. 2013. PMID: 23916595

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