Grosse-Hovest L - Search Results

1

Construction of optimized bispecific antibodies for selective activation of the death receptor CD95.

Herrmann T, Grosse-Hovest L, Otz T, Krammer PH, Rammensee HG, Jung G. Herrmann T, et al. Cancer Res. 2008 Feb 15;68(4):1221-7. doi: 10.1158/0008-5472.CAN-07-6175. Cancer Res. 2008. PMID: 18281499

2

Role of target antigen in bispecific-antibody-mediated killing of human glioblastoma cells: a pre-clinical study.

Pfosser A, Brandl M, Salih H, Grosse-Hovest L, Jung G. Pfosser A, et al. Int J Cancer. 1999 Feb 9;80(4):612-6. doi: 10.1002/(sici)1097-0215(19990209)80:4<612::aid-ijc21>3.0.co;2-k. Int J Cancer. 1999. PMID: 9935165

3

Tumor-growth inhibition with bispecific antibody fragments in a syngeneic mouse melanoma model: the role of targeted T-cell co-stimulation via CD28.

Grosse-Hovest L, Brandl M, Dohlsten M, Kalland T, Wilmanns W, Jung G. Grosse-Hovest L, et al. Int J Cancer. 1999 Jan 5;80(1):138-44. doi: 10.1002/(sici)1097-0215(19990105)80:1<138::aid-ijc25>3.0.co;2-j. Int J Cancer. 1999. PMID: 9935244

4

Bispecific antibody fragments with CD20 X CD28 specificity allow effective autologous and allogeneic T-cell activation against malignant cells in peripheral blood and bone marrow cultures from patients with B-cell lineage leukemia and lymphoma.

Brandl M, Grosse-Hovest L, Holler E, Kolb HJ, Jung G. Brandl M, et al. Exp Hematol. 1999 Aug;27(8):1264-70. doi: 10.1016/s0301-472x(99)00072-7. Exp Hematol. 1999. PMID: 10428503 Free article.

5

Target cell-restricted triggering of the CD95 (APO-1/Fas) death receptor with bispecific antibody fragments.

Jung G, Grosse-Hovest L, Krammer PH, Rammensee HG. Jung G, et al. Cancer Res. 2001 Mar 1;61(5):1846-8. Cancer Res. 2001. PMID: 11280736

6

A recombinant bispecific single-chain antibody induces targeted, supra-agonistic CD28-stimulation and tumor cell killing.

Grosse-Hovest L, Hartlapp I, Marwan W, Brem G, Rammensee HG, Jung G. Grosse-Hovest L, et al. Eur J Immunol. 2003 May;33(5):1334-40. doi: 10.1002/eji.200323322. Eur J Immunol. 2003. PMID: 12731059 Free article.

7

Cloned transgenic farm animals produce a bispecific antibody for T cell-mediated tumor cell killing.

Grosse-Hovest L, Müller S, Minoia R, Wolf E, Zakhartchenko V, Wenigerkind H, Lassnig C, Besenfelder U, Müller M, Lytton SD, Jung G, Brem G. Grosse-Hovest L, et al. Proc Natl Acad Sci U S A. 2004 May 4;101(18):6858-63. doi: 10.1073/pnas.0308487101. Epub 2004 Apr 22. Proc Natl Acad Sci U S A. 2004. PMID: 15105446 Free PMC article.

8

Supraagonistic, bispecific single-chain antibody purified from the serum of cloned, transgenic cows induces T-cell-mediated killing of glioblastoma cells in vitro and in vivo.

Grosse-Hovest L, Wick W, Minoia R, Weller M, Rammensee HG, Brem G, Jung G. Grosse-Hovest L, et al. Int J Cancer. 2005 Dec 20;117(6):1060-4. doi: 10.1002/ijc.21294. Int J Cancer. 2005. PMID: 16003729

9

Stimulus dependence of the action of small-molecule inhibitors in the CD3/CD28 signalling network.

Köhler K, Ganser A, André T, Roth G, Grosse-Hovest L, Jung G, Brock R. Köhler K, et al. ChemMedChem. 2008 Sep;3(9):1404-11. doi: 10.1002/cmdc.200800134. ChemMedChem. 2008. PMID: 18604819

10

A bispecific single-chain antibody that mediates target cell-restricted, supra-agonistic CD28 stimulation and killing of lymphoma cells.

Otz T, Grosse-Hovest L, Hofmann M, Rammensee HG, Jung G. Otz T, et al. Leukemia. 2009 Jan;23(1):71-7. doi: 10.1038/leu.2008.271. Epub 2008 Oct 2. Leukemia. 2009. PMID: 18830257

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