Chen T - Search Results

1

A methyl-CpG-binding protein 2-enhanced green fluorescent protein reporter mouse model provides a new tool for studying the neuronal basis of Rett syndrome.

Schmid RS, Tsujimoto N, Qu Q, Lei H, Li E, Chen T, Blaustein CS. Schmid RS, et al. Among authors: chen t. Neuroreport. 2008 Mar 5;19(4):393-8. doi: 10.1097/WNR.0b013e3282f5661c. Neuroreport. 2008. PMID: 18287934

2

The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin.

Chen T, Tsujimoto N, Li E. Chen T, et al. Mol Cell Biol. 2004 Oct;24(20):9048-58. doi: 10.1128/MCB.24.20.9048-9058.2004. Mol Cell Biol. 2004. PMID: 15456878 Free PMC article.

3

Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome.

Ueda Y, Okano M, Williams C, Chen T, Georgopoulos K, Li E. Ueda Y, et al. Among authors: chen t. Development. 2006 Mar;133(6):1183-92. doi: 10.1242/dev.02293. Development. 2006. PMID: 16501171

4

Structure and function of eukaryotic DNA methyltransferases.

Chen T, Li E. Chen T, et al. Curr Top Dev Biol. 2004;60:55-89. doi: 10.1016/S0070-2153(04)60003-2. Curr Top Dev Biol. 2004. PMID: 15094296 Review.

5

A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation.

Chen T, Ueda Y, Xie S, Li E. Chen T, et al. J Biol Chem. 2002 Oct 11;277(41):38746-54. doi: 10.1074/jbc.M205312200. Epub 2002 Jul 22. J Biol Chem. 2002. PMID: 12138111 Free article.

6

Ring1b-mediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation.

Fang J, Chen T, Chadwick B, Li E, Zhang Y. Fang J, et al. Among authors: chen t. J Biol Chem. 2004 Dec 17;279(51):52812-5. doi: 10.1074/jbc.C400493200. Epub 2004 Oct 26. J Biol Chem. 2004. PMID: 15509584 Free article.

7

Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization.

Dodge JE, Okano M, Dick F, Tsujimoto N, Chen T, Wang S, Ueda Y, Dyson N, Li E. Dodge JE, et al. Among authors: chen t. J Biol Chem. 2005 May 6;280(18):17986-91. doi: 10.1074/jbc.M413246200. Epub 2005 Mar 8. J Biol Chem. 2005. PMID: 15757890 Free article.

8

KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints.

Ciccone DN, Su H, Hevi S, Gay F, Lei H, Bajko J, Xu G, Li E, Chen T. Ciccone DN, et al. Among authors: chen t. Nature. 2009 Sep 17;461(7262):415-8. doi: 10.1038/nature08315. Epub 2009 Sep 2. Nature. 2009. PMID: 19727073

9

Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells.

Chen T, Hevi S, Gay F, Tsujimoto N, He T, Zhang B, Ueda Y, Li E. Chen T, et al. Nat Genet. 2007 Mar;39(3):391-6. doi: 10.1038/ng1982. Epub 2007 Feb 18. Nat Genet. 2007. PMID: 17322882

10

The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure.

Jones B, Su H, Bhat A, Lei H, Bajko J, Hevi S, Baltus GA, Kadam S, Zhai H, Valdez R, Gonzalo S, Zhang Y, Li E, Chen T. Jones B, et al. Among authors: chen t. PLoS Genet. 2008 Sep 12;4(9):e1000190. doi: 10.1371/journal.pgen.1000190. PLoS Genet. 2008. PMID: 18787701 Free PMC article.

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