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Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group.
Schwab M, Zanger UM, Marx C, Schaeffeler E, Klein K, Dippon J, Kerb R, Blievernicht J, Fischer J, Hofmann U, Bokemeyer C, Eichelbaum M; German 5-FU Toxicity Study Group. Schwab M, et al. Among authors: kerb r. J Clin Oncol. 2008 May 1;26(13):2131-8. doi: 10.1200/JCO.2006.10.4182. Epub 2008 Feb 25. J Clin Oncol. 2008. PMID: 18299612 Clinical Trial.
High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1).
Niemi M, Schaeffeler E, Lang T, Fromm MF, Neuvonen M, Kyrklund C, Backman JT, Kerb R, Schwab M, Neuvonen PJ, Eichelbaum M, Kivistö KT. Niemi M, et al. Among authors: kerb r. Pharmacogenetics. 2004 Jul;14(7):429-40. doi: 10.1097/01.fpc.0000114750.08559.32. Pharmacogenetics. 2004. PMID: 15226675
Variability in human hepatic MRP4 expression: influence of cholestasis and genotype.
Gradhand U, Lang T, Schaeffeler E, Glaeser H, Tegude H, Klein K, Fritz P, Jedlitschky G, Kroemer HK, Bachmakov I, Anwald B, Kerb R, Zanger UM, Eichelbaum M, Schwab M, Fromm MF. Gradhand U, et al. Among authors: kerb r. Pharmacogenomics J. 2008 Feb;8(1):42-52. doi: 10.1038/sj.tpj.6500451. Epub 2007 Apr 3. Pharmacogenomics J. 2008. PMID: 17404579
Data-driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment.
Fendt R, Hofmann U, Schneider ARP, Schaeffeler E, Burghaus R, Yilmaz A, Blank LM, Kerb R, Lippert J, Schlender JF, Schwab M, Kuepfer L. Fendt R, et al. Among authors: kerb r. CPT Pharmacometrics Syst Pharmacol. 2021 Jul;10(7):782-793. doi: 10.1002/psp4.12646. Epub 2021 Jun 26. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34053199 Free PMC article. Clinical Trial.
Simultaneous quantification of mefloquine (+)- and (-)-enantiomers and the carboxy metabolite in dried blood spots by liquid chromatography/tandem mass spectrometry.
Geditz MC, Lindner W, Lämmerhofer M, Heinkele G, Kerb R, Ramharter M, Schwab M, Hofmann U. Geditz MC, et al. Among authors: kerb r. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Oct 1;968:32-9. doi: 10.1016/j.jchromb.2013.11.035. Epub 2013 Nov 25. J Chromatogr B Analyt Technol Biomed Life Sci. 2014. PMID: 24315337
Low heritability in pharmacokinetics of talinolol: a pharmacogenetic twin study on the heritability of the pharmacokinetics of talinolol, a putative probe drug of MDR1 and other membrane transporters.
Matthaei J, Tzvetkov MV, Gal V, Sachse-Seeboth C, Sehrt D, Hjelmborg JB, Hofmann U, Schwab M, Kerb R, Brockmöller J. Matthaei J, et al. Among authors: kerb r. Genome Med. 2016 Nov 8;8(1):119. doi: 10.1186/s13073-016-0372-2. Genome Med. 2016. PMID: 27825374 Free PMC article. Clinical Trial.
Translational learning from clinical studies predicts drug pharmacokinetics across patient populations.
Krauss M, Hofmann U, Schafmayer C, Igel S, Schlender J, Mueller C, Brosch M, von Schoenfels W, Erhart W, Schuppert A, Block M, Schaeffeler E, Boehmer G, Goerlitz L, Hoecker J, Lippert J, Kerb R, Hampe J, Kuepfer L, Schwab M. Krauss M, et al. Among authors: kerb r. NPJ Syst Biol Appl. 2017 Mar 28;3:11. doi: 10.1038/s41540-017-0012-5. eCollection 2017. NPJ Syst Biol Appl. 2017. PMID: 28649438 Free PMC article.
66 results