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Immunotherapeutic approach to reduce senescent cells and alleviate senescence-associated secretory phenotype in mice.
Shrestha N, Chaturvedi P, Zhu X, Dee MJ, George V, Janney C, Egan JO, Liu B, Foster M, Marsala L, Wong P, Cubitt CC, Foltz JA, Tran J, Schappe T, Hsiao K, Leclerc GM, You L, Echeverri C, Spanoudis C, Carvalho A, Kanakaraj L, Gilkes C, Encalada N, Kong L, Wang M, Fang B, Wang Z, Jiao JA, Muniz GJ, Jeng EK, Valdivieso N, Li L, Deth R, Berrien-Elliott MM, Fehniger TA, Rhode PR, Wong HC. Shrestha N, et al. Among authors: schappe t. Aging Cell. 2023 May;22(5):e13806. doi: 10.1111/acel.13806. Epub 2023 Mar 26. Aging Cell. 2023. PMID: 36967480 Free PMC article.
Induced CD8α identifies human NK cells with enhanced proliferative fitness and modulates NK cell activation.
Cubitt CC, Wong P, Dorando HK, Foltz JA, Tran J, Marsala L, Marin ND, Foster M, Schappe T, Fatima H, Becker-Hapak M, Zhou AY, Hwang K, Jacobs MT, Russler-Germain DA, Mace EM, Berrien-Elliott MM, Payton JE, Fehniger TA. Cubitt CC, et al. Among authors: schappe t. J Clin Invest. 2024 May 28;134(15):e173602. doi: 10.1172/JCI173602. J Clin Invest. 2024. PMID: 38805302 Free PMC article.
Genetic ablation of calcium-independent phospholipase A2gamma prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation.
Mancuso DJ, Sims HF, Yang K, Kiebish MA, Su X, Jenkins CM, Guan S, Moon SH, Pietka T, Nassir F, Schappe T, Moore K, Han X, Abumrad NA, Gross RW. Mancuso DJ, et al. Among authors: schappe t. J Biol Chem. 2010 Nov 19;285(47):36495-510. doi: 10.1074/jbc.M110.115766. Epub 2010 Sep 3. J Biol Chem. 2010. PMID: 20817734 Free PMC article.
MicroRNA-142 Is Critical for the Homeostasis and Function of Type 1 Innate Lymphoid Cells.
Berrien-Elliott MM, Sun Y, Neal C, Ireland A, Trissal MC, Sullivan RP, Wagner JA, Leong JW, Wong P, Mah-Som AY, Wong TN, Schappe T, Keppel CR, Cortez VS, Stamatiades EG, Li MO, Colonna M, Link DC, French AR, Cooper MA, Wang WL, Boldin MP, Reddy P, Fehniger TA. Berrien-Elliott MM, et al. Among authors: schappe t. Immunity. 2019 Sep 17;51(3):479-490.e6. doi: 10.1016/j.immuni.2019.06.016. Epub 2019 Aug 8. Immunity. 2019. PMID: 31402259 Free PMC article.
Stage-Specific Requirement for Eomes in Mature NK Cell Homeostasis and Cytotoxicity.
Wagner JA, Wong P, Schappe T, Berrien-Elliott MM, Cubitt C, Jaeger N, Lee M, Keppel CR, Marin ND, Foltz JA, Marsala L, Neal CC, Sullivan RP, Schneider SE, Keppel MP, Saucier N, Cooper MA, Fehniger TA. Wagner JA, et al. Among authors: schappe t. Cell Rep. 2020 Jun 2;31(9):107720. doi: 10.1016/j.celrep.2020.107720. Cell Rep. 2020. PMID: 32492428 Free PMC article.
PTEN regulates natural killer cell trafficking in vivo.
Leong JW, Schneider SE, Sullivan RP, Parikh BA, Anthony BA, Singh A, Jewell BA, Schappe T, Wagner JA, Link DC, Yokoyama WM, Fehniger TA. Leong JW, et al. Among authors: schappe t. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E700-9. doi: 10.1073/pnas.1413886112. Epub 2015 Feb 2. Proc Natl Acad Sci U S A. 2015. PMID: 25646418 Free PMC article.
39 results