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Endothelial arginase II: a novel target for the treatment of atherosclerosis.
Ryoo S, Gupta G, Benjo A, Lim HK, Camara A, Sikka G, Lim HK, Sohi J, Santhanam L, Soucy K, Tuday E, Baraban E, Ilies M, Gerstenblith G, Nyhan D, Shoukas A, Christianson DW, Alp NJ, Champion HC, Huso D, Berkowitz DE. Ryoo S, et al. Among authors: sikka g. Circ Res. 2008 Apr 25;102(8):923-32. doi: 10.1161/CIRCRESAHA.107.169573. Epub 2008 Feb 28. Circ Res. 2008. PMID: 18309100
Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.
Kim JH, Bugaj LJ, Oh YJ, Bivalacqua TJ, Ryoo S, Soucy KG, Santhanam L, Webb A, Camara A, Sikka G, Nyhan D, Shoukas AA, Ilies M, Christianson DW, Champion HC, Berkowitz DE. Kim JH, et al. Among authors: sikka g. J Appl Physiol (1985). 2009 Oct;107(4):1249-57. doi: 10.1152/japplphysiol.91393.2008. Epub 2009 Aug 6. J Appl Physiol (1985). 2009. PMID: 19661445 Free PMC article.
Decreased S-nitrosylation of tissue transglutaminase contributes to age-related increases in vascular stiffness.
Santhanam L, Tuday EC, Webb AK, Dowzicky P, Kim JH, Oh YJ, Sikka G, Kuo M, Halushka MK, Macgregor AM, Dunn J, Gutbrod S, Yin D, Shoukas A, Nyhan D, Flavahan NA, Belkin AM, Berkowitz DE. Santhanam L, et al. Among authors: sikka g. Circ Res. 2010 Jul 9;107(1):117-25. doi: 10.1161/CIRCRESAHA.109.215228. Epub 2010 May 20. Circ Res. 2010. PMID: 20489165
Transcriptional regulation of endothelial arginase 2 by histone deacetylase 2.
Pandey D, Sikka G, Bergman Y, Kim JH, Ryoo S, Romer L, Berkowitz D. Pandey D, et al. Among authors: sikka g. Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1556-1566. doi: 10.1161/ATVBAHA.114.303685. Epub 2014 May 15. Arterioscler Thromb Vasc Biol. 2014. PMID: 24833798 Free PMC article.
Restoring leptin signaling reduces hyperlipidemia and improves vascular stiffness induced by chronic intermittent hypoxia.
Yang R, Sikka G, Larson J, Watts VL, Niu X, Ellis CL, Miller KL, Camara A, Reinke C, Savransky V, Polotsky VY, O'Donnell CP, Berkowitz DE, Barouch LA. Yang R, et al. Among authors: sikka g. Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1467-76. doi: 10.1152/ajpheart.00604.2009. Epub 2011 Jan 28. Am J Physiol Heart Circ Physiol. 2011. PMID: 21278136 Free PMC article.
39 results