Murphy MM - Search Results

1

DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination.

Franco S, Murphy MM, Li G, Borjeson T, Boboila C, Alt FW. Franco S, et al. Among authors: murphy mm. J Exp Med. 2008 Mar 17;205(3):557-64. doi: 10.1084/jem.20080044. Epub 2008 Mar 3. J Exp Med. 2008. PMID: 18316419 Free PMC article.

2

Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination.

Li G, Alt FW, Cheng HL, Brush JW, Goff PH, Murphy MM, Franco S, Zhang Y, Zha S. Li G, et al. Among authors: murphy mm. Mol Cell. 2008 Sep 5;31(5):631-40. doi: 10.1016/j.molcel.2008.07.017. Mol Cell. 2008. PMID: 18775323 Free PMC article.

3

IgH class switching and translocations use a robust non-classical end-joining pathway.

Yan CT, Boboila C, Souza EK, Franco S, Hickernell TR, Murphy M, Gumaste S, Geyer M, Zarrin AA, Manis JP, Rajewsky K, Alt FW. Yan CT, et al. Nature. 2007 Sep 27;449(7161):478-82. doi: 10.1038/nature06020. Epub 2007 Aug 22. Nature. 2007. PMID: 17713479

4

Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching.

Wang JH, Alt FW, Gostissa M, Datta A, Murphy M, Alimzhanov MB, Coakley KM, Rajewsky K, Manis JP, Yan CT. Wang JH, et al. J Exp Med. 2008 Dec 22;205(13):3079-90. doi: 10.1084/jem.20082271. Epub 2008 Dec 8. J Exp Med. 2008. PMID: 19064702 Free PMC article.

5

Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability.

Schenten D, Kracker S, Esposito G, Franco S, Klein U, Murphy M, Alt FW, Rajewsky K. Schenten D, et al. J Exp Med. 2009 Feb 16;206(2):477-90. doi: 10.1084/jem.20080669. Epub 2009 Feb 9. J Exp Med. 2009. PMID: 19204108 Free PMC article.

6

ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification.

Zha S, Bassing CH, Sanda T, Brush JW, Patel H, Goff PH, Murphy MM, Tepsuporn S, Gatti RA, Look AT, Alt FW. Zha S, et al. Among authors: murphy mm. J Exp Med. 2010 Jul 5;207(7):1369-80. doi: 10.1084/jem.20100285. Epub 2010 Jun 21. J Exp Med. 2010. PMID: 20566716 Free PMC article.

7

Aberrant V(D)J recombination is not required for rapid development of H2ax/p53-deficient thymic lymphomas with clonal translocations.

Bassing CH, Ranganath S, Murphy M, Savic V, Gleason M, Alt FW. Bassing CH, et al. Blood. 2008 Feb 15;111(4):2163-9. doi: 10.1182/blood-2007-08-104760. Epub 2007 Sep 13. Blood. 2008. PMID: 17855626 Free PMC article.

8

XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice.

Yan CT, Kaushal D, Murphy M, Zhang Y, Datta A, Chen C, Monroe B, Mostoslavsky G, Coakley K, Gao Y, Mills KD, Fazeli AP, Tepsuporn S, Hall G, Mulligan R, Fox E, Bronson R, De Girolami U, Lee C, Alt FW. Yan CT, et al. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7378-83. doi: 10.1073/pnas.0601938103. Epub 2006 May 2. Proc Natl Acad Sci U S A. 2006. PMID: 16670198 Free PMC article.

9

Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress.

Chua KF, Mostoslavsky R, Lombard DB, Pang WW, Saito S, Franco S, Kaushal D, Cheng HL, Fischer MR, Stokes N, Murphy MM, Appella E, Alt FW. Chua KF, et al. Among authors: murphy mm. Cell Metab. 2005 Jul;2(1):67-76. doi: 10.1016/j.cmet.2005.06.007. Cell Metab. 2005. PMID: 16054100 Free article.

10

H2AX prevents DNA breaks from progressing to chromosome breaks and translocations.

Franco S, Gostissa M, Zha S, Lombard DB, Murphy MM, Zarrin AA, Yan C, Tepsuporn S, Morales JC, Adams MM, Lou Z, Bassing CH, Manis JP, Chen J, Carpenter PB, Alt FW. Franco S, et al. Among authors: murphy mm. Mol Cell. 2006 Jan 20;21(2):201-14. doi: 10.1016/j.molcel.2006.01.005. Mol Cell. 2006. PMID: 16427010 Free article.

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