Duff KE - Search Results

1

Interplay between cyclin-dependent kinase 5 and glycogen synthase kinase 3 beta mediated by neuregulin signaling leads to differential effects on tau phosphorylation and amyloid precursor protein processing.

Wen Y, Planel E, Herman M, Figueroa HY, Wang L, Liu L, Lau LF, Yu WH, Duff KE. Wen Y, et al. Among authors: duff ke. J Neurosci. 2008 Mar 5;28(10):2624-32. doi: 10.1523/JNEUROSCI.5245-07.2008. J Neurosci. 2008. PMID: 18322105 Free PMC article.

2

Novel therapeutic approach for the treatment of Alzheimer's disease by peripheral administration of agents with an affinity to beta-amyloid.

Matsuoka Y, Saito M, LaFrancois J, Saito M, Gaynor K, Olm V, Wang L, Casey E, Lu Y, Shiratori C, Lemere C, Duff K. Matsuoka Y, et al. J Neurosci. 2003 Jan 1;23(1):29-33. doi: 10.1523/JNEUROSCI.23-01-00029.2003. J Neurosci. 2003. PMID: 12514198 Free PMC article.

3

Cdk5 is a key factor in tau aggregation and tangle formation in vivo.

Noble W, Olm V, Takata K, Casey E, Mary O, Meyerson J, Gaynor K, LaFrancois J, Wang L, Kondo T, Davies P, Burns M, Veeranna, Nixon R, Dickson D, Matsuoka Y, Ahlijanian M, Lau LF, Duff K. Noble W, et al. Neuron. 2003 May 22;38(4):555-65. doi: 10.1016/s0896-6273(03)00259-9. Neuron. 2003. PMID: 12765608 Free article.

4

Presenilin redistribution associated with aberrant cholesterol transport enhances beta-amyloid production in vivo.

Burns M, Gaynor K, Olm V, Mercken M, LaFrancois J, Wang L, Mathews PM, Noble W, Matsuoka Y, Duff K. Burns M, et al. J Neurosci. 2003 Jul 2;23(13):5645-9. doi: 10.1523/JNEUROSCI.23-13-05645.2003. J Neurosci. 2003. PMID: 12843267 Free PMC article.

5

Application of a non-linear image registration algorithm to quantitative analysis of T2 relaxation time in transgenic mouse models of AD pathology.

Falangola MF, Ardekani BA, Lee SP, Babb JS, Bogart A, Dyakin VV, Nixon R, Duff K, Helpern JA. Falangola MF, et al. J Neurosci Methods. 2005 May 15;144(1):91-7. doi: 10.1016/j.jneumeth.2004.10.012. Epub 2004 Dec 7. J Neurosci Methods. 2005. PMID: 15848243 Free PMC article.

6

Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo.

Noble W, Planel E, Zehr C, Olm V, Meyerson J, Suleman F, Gaynor K, Wang L, LaFrancois J, Feinstein B, Burns M, Krishnamurthy P, Wen Y, Bhat R, Lewis J, Dickson D, Duff K. Noble W, et al. Proc Natl Acad Sci U S A. 2005 May 10;102(19):6990-5. doi: 10.1073/pnas.0500466102. Epub 2005 May 2. Proc Natl Acad Sci U S A. 2005. PMID: 15867159 Free PMC article.

7

Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.

Andorfer C, Acker CM, Kress Y, Hof PR, Duff K, Davies P. Andorfer C, et al. J Neurosci. 2005 Jun 1;25(22):5446-54. doi: 10.1523/JNEUROSCI.4637-04.2005. J Neurosci. 2005. PMID: 15930395 Free PMC article.

8

Untangling memory deficits.

Duff K, Planel E. Duff K, et al. Nat Med. 2005 Aug;11(8):826-7. doi: 10.1038/nm0805-826. Nat Med. 2005. PMID: 16079873 No abstract available.

9

Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease.

Yu WH, Cuervo AM, Kumar A, Peterhoff CM, Schmidt SD, Lee JH, Mohan PS, Mercken M, Farmery MR, Tjernberg LO, Jiang Y, Duff K, Uchiyama Y, Näslund J, Mathews PM, Cataldo AM, Nixon RA. Yu WH, et al. J Cell Biol. 2005 Oct 10;171(1):87-98. doi: 10.1083/jcb.200505082. Epub 2005 Oct 3. J Cell Biol. 2005. PMID: 16203860 Free PMC article.

10

Cholesterol distribution, not total levels, correlate with altered amyloid precursor protein processing in statin-treated mice.

Burns MP, Igbavboa U, Wang L, Wood WG, Duff K. Burns MP, et al. Neuromolecular Med. 2006;8(3):319-28. doi: 10.1385/nmm:8:3:319. Neuromolecular Med. 2006. PMID: 16775383

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