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Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics.
Jarnicki AG, Conroy H, Brereton C, Donnelly G, Toomey D, Walsh K, Sweeney C, Leavy O, Fletcher J, Lavelle EC, Dunne P, Mills KH. Jarnicki AG, et al. Among authors: fletcher j. J Immunol. 2008 Mar 15;180(6):3797-806. doi: 10.4049/jimmunol.180.6.3797. J Immunol. 2008. PMID: 18322186
Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells.
Taams LS, Vukmanovic-Stejic M, Smith J, Dunne PJ, Fletcher JM, Plunkett FJ, Ebeling SB, Lombardi G, Rustin MH, Bijlsma JW, Lafeber FP, Salmon M, Akbar AN. Taams LS, et al. Among authors: fletcher jm. Eur J Immunol. 2002 Jun;32(6):1621-30. doi: 10.1002/1521-4141(200206)32:6<1621::AID-IMMU1621>3.0.CO;2-Q. Eur J Immunol. 2002. PMID: 12115645 Free article.
OAS1: a multiple sclerosis susceptibility gene that influences disease severity.
O'Brien M, Lonergan R, Costelloe L, O'Rourke K, Fletcher JM, Kinsella K, Sweeney C, Antonelli G, Mills KH, O'Farrelly C, Hutchinson M, Tubridy N. O'Brien M, et al. Among authors: fletcher jm. Neurology. 2010 Aug 3;75(5):411-8. doi: 10.1212/WNL.0b013e3181ebdd2b. Neurology. 2010. PMID: 20679634
4,279 results