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Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1.
Fätkenheuer G, Pozniak AL, Johnson MA, Plettenberg A, Staszewski S, Hoepelman AI, Saag MS, Goebel FD, Rockstroh JK, Dezube BJ, Jenkins TM, Medhurst C, Sullivan JF, Ridgway C, Abel S, James IT, Youle M, van der Ryst E. Fätkenheuer G, et al. Among authors: van der ryst e. Nat Med. 2005 Nov;11(11):1170-2. doi: 10.1038/nm1319. Epub 2005 Oct 5. Nat Med. 2005. PMID: 16205738
Emergence of CXCR4-using human immunodeficiency virus type 1 (HIV-1) variants in a minority of HIV-1-infected patients following treatment with the CCR5 antagonist maraviroc is from a pretreatment CXCR4-using virus reservoir.
Westby M, Lewis M, Whitcomb J, Youle M, Pozniak AL, James IT, Jenkins TM, Perros M, van der Ryst E. Westby M, et al. Among authors: van der ryst e. J Virol. 2006 May;80(10):4909-20. doi: 10.1128/JVI.80.10.4909-4920.2006. J Virol. 2006. PMID: 16641282 Free PMC article. Clinical Trial.
CCR5 pharmacology methodologies and associated applications.
Mansfield R, Able S, Griffin P, Irvine B, James I, Macartney M, Miller K, Mills J, Napier C, Navratilova I, Perros M, Rickett G, Root H, van der Ryst E, Westby M, Dorr P. Mansfield R, et al. Among authors: van der ryst e. Methods Enzymol. 2009;460:17-55. doi: 10.1016/S0076-6879(09)05202-1. Methods Enzymol. 2009. PMID: 19446719
Pharmacokinetics, Safety and Efficacy of Maraviroc in Treatment-experienced Pediatric Patients Infected With CCR5-Tropic HIV-1.
Giaquinto C, Mawela MP, Chokephaibulkit K, Negra MD, Mitha IH, Fourie J, Fang A, van der Ryst E, Valluri SR, Vourvahis M, Zhang-Roper RY, Craig C, McFadyen L, Clark A, Heera J. Giaquinto C, et al. Among authors: van der ryst e. Pediatr Infect Dis J. 2018 May;37(5):459-465. doi: 10.1097/INF.0000000000001808. Pediatr Infect Dis J. 2018. PMID: 29023357 Free PMC article.
72 results