Sinclair PB - Search Results

1

The facultative heterochromatin of the inactive X chromosome has a distinctive condensed ultrastructure.

Rego A, Sinclair PB, Tao W, Kireev I, Belmont AS. Rego A, et al. Among authors: sinclair pb. J Cell Sci. 2008 Apr 1;121(Pt 7):1119-27. doi: 10.1242/jcs.026104. Epub 2008 Mar 11. J Cell Sci. 2008. PMID: 18334550

2

Dynamic plasticity of large-scale chromatin structure revealed by self-assembly of engineered chromosome regions.

Sinclair P, Bian Q, Plutz M, Heard E, Belmont AS. Sinclair P, et al. J Cell Biol. 2010 Sep 6;190(5):761-76. doi: 10.1083/jcb.200912167. J Cell Biol. 2010. PMID: 20819934 Free PMC article.

3

Insights into interphase large-scale chromatin structure from analysis of engineered chromosome regions.

Belmont AS, Hu Y, Sinclair PB, Wu W, Bian Q, Kireev I. Belmont AS, et al. Among authors: sinclair pb. Cold Spring Harb Symp Quant Biol. 2010;75:453-60. doi: 10.1101/sqb.2010.75.050. Epub 2011 Apr 5. Cold Spring Harb Symp Quant Biol. 2010. PMID: 21467143 Free PMC article.

4

Disruption to the FOXO-PRDM1 axis resulting from deletions of chromosome 6 in acute lymphoblastic leukaemia.

Sinclair PB, Cranston RE, Raninga P, Cheng J, Hanna R, Hawking Z, Hair S, Ryan SL, Enshaei A, Nakjang S, Rand V, Blair HJ, Moorman AV, Heidenreich O, Harrison CJ. Sinclair PB, et al. Leukemia. 2023 Mar;37(3):636-649. doi: 10.1038/s41375-023-01816-0. Epub 2023 Jan 20. Leukemia. 2023. PMID: 36670235 Free PMC article.

5

SH2B3 inactivation through CN-LOH 12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain.

Sinclair PB, Ryan S, Bashton M, Hollern S, Hanna R, Case M, Schwalbe EC, Schwab CJ, Cranston RE, Young BD, Irving JAE, Vora AJ, Moorman AV, Harrison CJ. Sinclair PB, et al. Leukemia. 2019 Aug;33(8):1881-1894. doi: 10.1038/s41375-019-0412-1. Epub 2019 Feb 28. Leukemia. 2019. PMID: 30816328 Free PMC article.

6

Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.

Sinclair PB, Blair HH, Ryan SL, Buechler L, Cheng J, Clayton J, Hanna R, Hollern S, Hawking Z, Bashton M, Schwab CJ, Jones L, Russell LJ, Marr H, Carey P, Halsey C, Heidenreich O, Moorman AV, Harrison CJ. Sinclair PB, et al. Haematologica. 2018 Apr;103(4):634-644. doi: 10.3324/haematol.2017.172304. Epub 2018 Feb 15. Haematologica. 2018. PMID: 29449437 Free PMC article.

7

Analysis of a breakpoint cluster reveals insight into the mechanism of intrachromosomal amplification in a lymphoid malignancy.

Sinclair PB, Parker H, An Q, Rand V, Ensor H, Harrison CJ, Strefford JC. Sinclair PB, et al. Hum Mol Genet. 2011 Jul 1;20(13):2591-602. doi: 10.1093/hmg/ddr159. Epub 2011 Apr 12. Hum Mol Genet. 2011. PMID: 21487021

8

A fluorescence in situ hybridization map of 6q deletions in acute lymphocytic leukemia: identification and analysis of a candidate tumor suppressor gene.

Sinclair PB, Sorour A, Martineau M, Harrison CJ, Mitchell WA, O'Neill E, Foroni L. Sinclair PB, et al. Cancer Res. 2004 Jun 15;64(12):4089-98. doi: 10.1158/0008-5472.CAN-03-1871. Cancer Res. 2004. PMID: 15205317

9

Large deletions at the t(9;22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia.

Sinclair PB, Nacheva EP, Leversha M, Telford N, Chang J, Reid A, Bench A, Champion K, Huntly B, Green AR. Sinclair PB, et al. Blood. 2000 Feb 1;95(3):738-43. Blood. 2000. PMID: 10648381 Free article.

10

Comparative analysis of G-banding, chromosome painting, locus-specific fluorescence in situ hybridization, and comparative genomic hybridization in chronic myeloid leukemia blast crisis.

Gribble SM, Sinclair PB, Grace C, Green AR, Nacheva EP. Gribble SM, et al. Among authors: sinclair pb. Cancer Genet Cytogenet. 1999 May;111(1):7-17. doi: 10.1016/s0165-4608(98)00213-1. Cancer Genet Cytogenet. 1999. PMID: 10326584

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