Young SG - Search Results

1

Lipoprotein size and susceptibility to atherosclerosis--insights from genetically modified mouse models.

Véniant MM, Beigneux AP, Bensadoun A, Fong LG, Young SG. Véniant MM, et al. Among authors: young sg. Curr Drug Targets. 2008 Mar;9(3):174-89. doi: 10.2174/138945008783755629. Curr Drug Targets. 2008. PMID: 18336235 Free PMC article. Review.

2

Transgenic mice that overexpress mouse apolipoprotein B. Evidence that the DNA sequences controlling intestinal expression of the apolipoprotein B gene are distant from the structural gene.

McCormick SP, Ng JK, Véniant M, Borén J, Pierotti V, Flynn LM, Grass DS, ConnollyA, Young SG. McCormick SP, et al. Among authors: young sg. J Biol Chem. 1996 May 17;271(20):11963-70. doi: 10.1074/jbc.271.20.11963. J Biol Chem. 1996. PMID: 8662599 Free article.

3

Phenotypic analysis of mice expressing exclusively apolipoprotein B48 or apolipoprotein B100.

Farese RV Jr, Véniant MM, Cham CM, Flynn LM, Pierotti V, Loring JF, Traber M, Ruland S, Stokowski RS, Huszar D, Young SG. Farese RV Jr, et al. Among authors: young sg. Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6393-8. doi: 10.1073/pnas.93.13.6393. Proc Natl Acad Sci U S A. 1996. PMID: 8692825 Free PMC article.

4

Susceptibility to atherosclerosis in mice expressing exclusively apolipoprotein B48 or apolipoprotein B100.

Véniant MM, Pierotti V, Newland D, Cham CM, Sanan DA, Walzem RL, Young SG. Véniant MM, et al. Among authors: young sg. J Clin Invest. 1997 Jul 1;100(1):180-8. doi: 10.1172/JCI119511. J Clin Invest. 1997. PMID: 9202070 Free PMC article.

5

Apo B100-containing lipoproteins are secreted by the heart.

Borén J, Véniant MM, Young SG. Borén J, et al. Among authors: young sg. J Clin Invest. 1998 Mar 15;101(6):1197-202. doi: 10.1172/JCI1785. J Clin Invest. 1998. PMID: 9502759 Free PMC article.

6

Dual mechanisms for the low plasma levels of truncated apolipoprotein B proteins in familial hypobetalipoproteinemia. Analysis of a new mouse model with a nonsense mutation in the Apob gene.

Kim E, Cham CM, Véniant MM, Ambroziak P, Young SG. Kim E, et al. Among authors: young sg. J Clin Invest. 1998 Mar 15;101(6):1468-77. J Clin Invest. 1998. PMID: 9502790 Free PMC article.

7

Genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in the heart: evidence that the heart has the capacity to synthesize and secrete lipoproteins.

Nielsen LB, Véniant M, Borén J, Raabe M, Wong JS, Tam C, Flynn L, Vanni-Reyes T, Gunn MD, Goldberg IJ, Hamilton RL, Young SG. Nielsen LB, et al. Among authors: young sg. Circulation. 1998 Jul 7;98(1):13-6. doi: 10.1161/01.cir.98.1.13. Circulation. 1998. PMID: 9665054

8

Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes.

Raabe M, Flynn LM, Zlot CH, Wong JS, Véniant MM, Hamilton RL, Young SG. Raabe M, et al. Among authors: young sg. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8686-91. doi: 10.1073/pnas.95.15.8686. Proc Natl Acad Sci U S A. 1998. PMID: 9671739 Free PMC article.

9

A mouse model of human familial hypercholesterolemia: markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet.

Powell-Braxton L, Véniant M, Latvala RD, Hirano KI, Won WB, Ross J, Dybdal N, Zlot CH, Young SG, Davidson NO. Powell-Braxton L, et al. Among authors: young sg. Nat Med. 1998 Aug;4(8):934-8. doi: 10.1038/nm0898-934. Nat Med. 1998. PMID: 9701246

10

Lipoprotein clearance mechanisms in LDL receptor-deficient "Apo-B48-only" and "Apo-B100-only" mice.

Véniant MM, Zlot CH, Walzem RL, Pierotti V, Driscoll R, Dichek D, Herz J, Young SG. Véniant MM, et al. Among authors: young sg. J Clin Invest. 1998 Oct 15;102(8):1559-68. doi: 10.1172/JCI4164. J Clin Invest. 1998. PMID: 9788969 Free PMC article.

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