Hagan MP - Search Results

1

Transient exposure of carcinoma cells to RAS/MEK inhibitors and UCN-01 causes cell death in vitro and in vivo.

Hamed H, Hawkins W, Mitchell C, Gilfor D, Zhang G, Pei XY, Dai Y, Hagan MP, Roberts JD, Yacoub A, Grant S, Dent P. Hamed H, et al. Among authors: hagan mp. Mol Cancer Ther. 2008 Mar;7(3):616-29. doi: 10.1158/1535-7163.MCT-07-2376. Mol Cancer Ther. 2008. PMID: 18347148

2

Pharmocologic inhibitors of the mitogen activated protein kinase cascade have the potential to interact with ionizing radiation exposure to induce cell death in carcinoma cells by multiple mechanisms.

Qiao L, Yacoub A, McKinstry R, Park JS, Caron R, Fisher PB, Hagan MP, Grant S, Dent P. Qiao L, et al. Among authors: hagan mp. Cancer Biol Ther. 2002 Mar-Apr;1(2):168-76. doi: 10.4161/cbt.64. Cancer Biol Ther. 2002. PMID: 12170777 Free article.

3

Inhibitors of MEK1/2 interact with UCN-01 to induce apoptosis and reduce colony formation in mammary and prostate carcinoma cells.

McKinstry R, Qiao L, Yacoub A, Dai Y, Decker R, Holt S, Hagan MP, Grant S, Dent P. McKinstry R, et al. Among authors: hagan mp. Cancer Biol Ther. 2002 May-Jun;1(3):243-53. doi: 10.4161/cbt.75. Cancer Biol Ther. 2002. PMID: 12432271 Free article.

4

H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent.

Carón RW, Yacoub A, Zhu X, Mitchell C, Han SI, Sasazuki T, Shirasawa S, Hagan MP, Grant S, Dent P. Carón RW, et al. Among authors: hagan mp. Mol Cancer Ther. 2005 Feb;4(2):243-55. Mol Cancer Ther. 2005. PMID: 15713896

5

Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1, and AKT and the effect of therapeutic kinase inhibitors on cell survival.

Carón RW, Yacoub A, Li M, Zhu X, Mitchell C, Hong Y, Hawkins W, Sasazuki T, Shirasawa S, Kozikowski AP, Dennis PA, Hagan MP, Grant S, Dent P. Carón RW, et al. Among authors: hagan mp. Mol Cancer Ther. 2005 Feb;4(2):257-70. Mol Cancer Ther. 2005. PMID: 15713897

6

MEK1/2 inhibition promotes Taxotere lethality in mammary tumors in vivo.

Yacoub A, Gilfor D, Hawkins W, Park MA, Hanna D, Hagan MP, Curiel DT, Fisher PB, Grant S, Dent P. Yacoub A, et al. Among authors: hagan mp. Cancer Biol Ther. 2006 Oct;5(10):1332-9. doi: 10.4161/cbt.5.10.3215. Epub 2006 Oct 15. Cancer Biol Ther. 2006. PMID: 16957420 Free article.

7

Human chorionic gonadotropin modulates prostate cancer cell survival after irradiation or HMG CoA reductase inhibitor treatment.

Yacoub A, Hawkins W, Hanna D, Young H, Park MA, Grant M, Roberts JD, Curiel DT, Fisher PB, Valerie K, Grant S, Hagan MP, Dent P. Yacoub A, et al. Among authors: hagan mp. Mol Pharmacol. 2007 Jan;71(1):259-75. doi: 10.1124/mol.106.031153. Epub 2006 Oct 18. Mol Pharmacol. 2007. PMID: 17050804

8

Radiation-induced cell signaling: inside-out and outside-in.

Valerie K, Yacoub A, Hagan MP, Curiel DT, Fisher PB, Grant S, Dent P. Valerie K, et al. Among authors: hagan mp. Mol Cancer Ther. 2007 Mar;6(3):789-801. doi: 10.1158/1535-7163.MCT-06-0596. Mol Cancer Ther. 2007. PMID: 17363476 Review.

9

Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling.

Mitchell C, Kabolizadeh P, Ryan J, Roberts JD, Yacoub A, Curiel DT, Fisher PB, Hagan MP, Farrell NP, Grant S, Dent P. Mitchell C, et al. Among authors: hagan mp. Mol Pharmacol. 2007 Sep;72(3):704-14. doi: 10.1124/mol.107.038406. Epub 2007 Jun 19. Mol Pharmacol. 2007. PMID: 17578896

10

Human chorionic gonadotropin (hCG) interacts with lovastatin and ionizing radiation to modulate prostate cancer cell viability in vivo.

Hamed H, Mitchell C, Park MA, Hanna D, Martin AP, Harrison B, Hawkins W, Curiel DA, Fisher PB, Grant S, Yacoub A, Hagan MP, Dent P. Hamed H, et al. Among authors: hagan mp. Cancer Biol Ther. 2008 Apr;7(4):587-93. doi: 10.4161/cbt.7.4.5543. Epub 2008 Jan 8. Cancer Biol Ther. 2008. PMID: 18379195 Free article.

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