Yacoub A - Search Results

1

Transient exposure of carcinoma cells to RAS/MEK inhibitors and UCN-01 causes cell death in vitro and in vivo.

Hamed H, Hawkins W, Mitchell C, Gilfor D, Zhang G, Pei XY, Dai Y, Hagan MP, Roberts JD, Yacoub A, Grant S, Dent P. Hamed H, et al. Among authors: yacoub a. Mol Cancer Ther. 2008 Mar;7(3):616-29. doi: 10.1158/1535-7163.MCT-07-2376. Mol Cancer Ther. 2008. PMID: 18347148

2

Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways.

Park JS, Qiao L, Su ZZ, Hinman D, Willoughby K, McKinstry R, Yacoub A, Duigou GJ, Young CS, Grant S, Hagan MP, Ellis E, Fisher PB, Dent P. Park JS, et al. Among authors: yacoub a. Oncogene. 2001 May 31;20(25):3266-80. doi: 10.1038/sj.onc.1204258. Oncogene. 2001. PMID: 11423976

3

Hepatitis B virus X protein increases expression of p21(Cip-1/WAF1/MDA6) and p27(Kip-1) in primary mouse hepatocytes, leading to reduced cell cycle progression.

Qiao L, Leach K, McKinstry R, Gilfor D, Yacoub A, Park JS, Grant S, Hylemon PB, Fisher PB, Dent P. Qiao L, et al. Among authors: yacoub a. Hepatology. 2001 Nov;34(5):906-17. doi: 10.1053/jhep.2001.28886. Hepatology. 2001. PMID: 11679961

4

MAPK dependence of DNA damage repair: ionizing radiation and the induction of expression of the DNA repair genes XRCC1 and ERCC1 in DU145 human prostate carcinoma cells in a MEK1/2 dependent fashion.

Yacoub A, Park JS, Qiao L, Dent P, Hagan MP. Yacoub A, et al. Int J Radiat Biol. 2001 Oct;77(10):1067-78. doi: 10.1080/09553000110069317. Int J Radiat Biol. 2001. PMID: 11682011

5

Autocrine loops with positive feedback enable context-dependent cell signaling.

Shvartsman SY, Hagan MP, Yacoub A, Dent P, Wiley HS, Lauffenburger DA. Shvartsman SY, et al. Among authors: yacoub a. Am J Physiol Cell Physiol. 2002 Mar;282(3):C545-59. doi: 10.1152/ajpcell.00260.2001. Am J Physiol Cell Physiol. 2002. PMID: 11832340 Free article.

6

Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes.

Qiao L, Yacoub A, Studer E, Gupta S, Pei XY, Grant S, Hylemon PB, Dent P. Qiao L, et al. Among authors: yacoub a. Hepatology. 2002 Apr;35(4):779-89. doi: 10.1053/jhep.2002.32533. Hepatology. 2002. PMID: 11915023

7

Pharmocologic inhibitors of the mitogen activated protein kinase cascade have the potential to interact with ionizing radiation exposure to induce cell death in carcinoma cells by multiple mechanisms.

Qiao L, Yacoub A, McKinstry R, Park JS, Caron R, Fisher PB, Hagan MP, Grant S, Dent P. Qiao L, et al. Among authors: yacoub a. Cancer Biol Ther. 2002 Mar-Apr;1(2):168-76. doi: 10.4161/cbt.64. Cancer Biol Ther. 2002. PMID: 12170777 Free article.

8

Inhibitors of MEK1/2 interact with UCN-01 to induce apoptosis and reduce colony formation in mammary and prostate carcinoma cells.

McKinstry R, Qiao L, Yacoub A, Dai Y, Decker R, Holt S, Hagan MP, Grant S, Dent P. McKinstry R, et al. Among authors: yacoub a. Cancer Biol Ther. 2002 May-Jun;1(3):243-53. doi: 10.4161/cbt.75. Cancer Biol Ther. 2002. PMID: 12432271 Free article.

9

Stress and radiation-induced activation of multiple intracellular signaling pathways.

Dent P, Yacoub A, Contessa J, Caron R, Amorino G, Valerie K, Hagan MP, Grant S, Schmidt-Ullrich R. Dent P, et al. Among authors: yacoub a. Radiat Res. 2003 Mar;159(3):283-300. doi: 10.1667/0033-7587(2003)159[0283:sariao]2.0.co;2. Radiat Res. 2003. PMID: 12600231 Review.

10

Epidermal growth factor and ionizing radiation up-regulate the DNA repair genes XRCC1 and ERCC1 in DU145 and LNCaP prostate carcinoma through MAPK signaling.

Yacoub A, McKinstry R, Hinman D, Chung T, Dent P, Hagan MP. Yacoub A, et al. Radiat Res. 2003 Apr;159(4):439-52. doi: 10.1667/0033-7587(2003)159[0439:egfair]2.0.co;2. Radiat Res. 2003. PMID: 12643788

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