Shim H - Search Results

1

The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2.

Wang L, Xie C, Greggio E, Parisiadou L, Shim H, Sun L, Chandran J, Lin X, Lai C, Yang WJ, Moore DJ, Dawson TM, Dawson VL, Chiosis G, Cookson MR, Cai H. Wang L, et al. Among authors: shim h. J Neurosci. 2008 Mar 26;28(13):3384-91. doi: 10.1523/JNEUROSCI.0185-08.2008. J Neurosci. 2008. PMID: 18367605 Free PMC article.

2

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking.

Lai C, Xie C, McCormack SG, Chiang HC, Michalak MK, Lin X, Chandran J, Shim H, Shimoji M, Cookson MR, Huganir RL, Rothstein JD, Price DL, Wong PC, Martin LJ, Zhu JJ, Cai H. Lai C, et al. Among authors: shim h. J Neurosci. 2006 Nov 8;26(45):11798-806. doi: 10.1523/JNEUROSCI.2084-06.2006. J Neurosci. 2006. PMID: 17093100 Free PMC article.

3

Activation of protein kinase C modulates BACE1-mediated beta-secretase activity.

Wang L, Shim H, Xie C, Cai H. Wang L, et al. Among authors: shim h. Neurobiol Aging. 2008 Mar;29(3):357-67. doi: 10.1016/j.neurobiolaging.2006.11.001. Epub 2006 Dec 6. Neurobiol Aging. 2008. PMID: 17157415 Free PMC article.

4

The G59S mutation in p150(glued) causes dysfunction of dynactin in mice.

Lai C, Lin X, Chandran J, Shim H, Yang WJ, Cai H. Lai C, et al. Among authors: shim h. J Neurosci. 2007 Dec 19;27(51):13982-90. doi: 10.1523/JNEUROSCI.4226-07.2007. J Neurosci. 2007. PMID: 18094236 Free PMC article.

5

Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein.

Lin X, Parisiadou L, Gu XL, Wang L, Shim H, Sun L, Xie C, Long CX, Yang WJ, Ding J, Chen ZZ, Gallant PE, Tao-Cheng JH, Rudow G, Troncoso JC, Liu Z, Li Z, Cai H. Lin X, et al. Among authors: shim h. Neuron. 2009 Dec 24;64(6):807-27. doi: 10.1016/j.neuron.2009.11.006. Neuron. 2009. PMID: 20064389 Free PMC article.

6

Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1.

Lin X, Parisiadou L, Sgobio C, Liu G, Yu J, Sun L, Shim H, Gu XL, Luo J, Long CX, Ding J, Mateo Y, Sullivan PH, Wu LG, Goldstein DS, Lovinger D, Cai H. Lin X, et al. Among authors: shim h. J Neurosci. 2012 Jul 4;32(27):9248-64. doi: 10.1523/JNEUROSCI.1731-12.2012. J Neurosci. 2012. PMID: 22764233 Free PMC article.

7

Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress.

Cai H, Lin X, Xie C, Laird FM, Lai C, Wen H, Chiang HC, Shim H, Farah MH, Hoke A, Price DL, Wong PC. Cai H, et al. Among authors: shim h. J Neurosci. 2005 Aug 17;25(33):7567-74. doi: 10.1523/JNEUROSCI.1645-05.2005. J Neurosci. 2005. PMID: 16107644 Free PMC article.

8

Deficiency in the ALS2 gene does not affect the motor neuron degeneration in SOD1(G93A) transgenic mice.

Lin X, Shim H, Cai H. Lin X, et al. Among authors: shim h. Neurobiol Aging. 2007 Oct;28(10):1628-30. doi: 10.1016/j.neurobiolaging.2006.07.014. Epub 2006 Sep 12. Neurobiol Aging. 2007. PMID: 16973244 Free PMC article.

9

ALS2/alsin knockout mice and motor neuron diseases.

Cai H, Shim H, Lai C, Xie C, Lin X, Yang WJ, Chandran J. Cai H, et al. Among authors: shim h. Neurodegener Dis. 2008;5(6):359-66. doi: 10.1159/000151295. Epub 2008 Aug 20. Neurodegener Dis. 2008. PMID: 18714162 Free PMC article. Review.

10

Amyotrophic lateral sclerosis-related VAPB P56S mutation differentially affects the function and survival of corticospinal and spinal motor neurons.

Aliaga L, Lai C, Yu J, Chub N, Shim H, Sun L, Xie C, Yang WJ, Lin X, O'Donovan MJ, Cai H. Aliaga L, et al. Among authors: shim h. Hum Mol Genet. 2013 Nov 1;22(21):4293-305. doi: 10.1093/hmg/ddt279. Epub 2013 Jun 13. Hum Mol Genet. 2013. PMID: 23771029 Free PMC article.

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