Lu D - Search Results

1

Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism.

Ronnebaum SM, Joseph JW, Ilkayeva O, Burgess SC, Lu D, Becker TC, Sherry AD, Newgard CB. Ronnebaum SM, et al. Among authors: lu d. J Biol Chem. 2008 May 23;283(21):14248-56. doi: 10.1074/jbc.M800119200. Epub 2008 Apr 1. J Biol Chem. 2008. PMID: 18381287 Free PMC article.

2

Stimulus/secretion coupling factors in glucose-stimulated insulin secretion: insights gained from a multidisciplinary approach.

Newgard CB, Lu D, Jensen MV, Schissler J, Boucher A, Burgess S, Sherry AD. Newgard CB, et al. Among authors: lu d. Diabetes. 2002 Dec;51 Suppl 3:S389-93. doi: 10.2337/diabetes.51.2007.s389. Diabetes. 2002. PMID: 12475781 Review.

3

Biochemical mechanism of lipid-induced impairment of glucose-stimulated insulin secretion and reversal with a malate analogue.

Boucher A, Lu D, Burgess SC, Telemaque-Potts S, Jensen MV, Mulder H, Wang MY, Unger RH, Sherry AD, Newgard CB. Boucher A, et al. Among authors: lu d. J Biol Chem. 2004 Jun 25;279(26):27263-71. doi: 10.1074/jbc.M401167200. Epub 2004 Apr 7. J Biol Chem. 2004. PMID: 15073188 Free article.

4

The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells.

Schisler JC, Jensen PB, Taylor DG, Becker TC, Knop FK, Takekawa S, German M, Weir GC, Lu D, Mirmira RG, Newgard CB. Schisler JC, et al. Among authors: lu d. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7297-302. doi: 10.1073/pnas.0502168102. Epub 2005 May 9. Proc Natl Acad Sci U S A. 2005. PMID: 15883383 Free PMC article.

5

Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion.

Jensen MV, Joseph JW, Ilkayeva O, Burgess S, Lu D, Ronnebaum SM, Odegaard M, Becker TC, Sherry AD, Newgard CB. Jensen MV, et al. Among authors: lu d. J Biol Chem. 2006 Aug 4;281(31):22342-22351. doi: 10.1074/jbc.M604350200. Epub 2006 Jun 1. J Biol Chem. 2006. PMID: 16740637 Free article.

6

A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion.

Ronnebaum SM, Ilkayeva O, Burgess SC, Joseph JW, Lu D, Stevens RD, Becker TC, Sherry AD, Newgard CB, Jensen MV. Ronnebaum SM, et al. Among authors: lu d. J Biol Chem. 2006 Oct 13;281(41):30593-602. doi: 10.1074/jbc.M511908200. Epub 2006 Aug 15. J Biol Chem. 2006. PMID: 16912049 Free article.

7

Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets.

Ronnebaum SM, Jensen MV, Hohmeier HE, Burgess SC, Zhou YP, Qian S, MacNeil D, Howard A, Thornberry N, Ilkayeva O, Lu D, Sherry AD, Newgard CB. Ronnebaum SM, et al. Among authors: lu d. J Biol Chem. 2008 Oct 24;283(43):28909-17. doi: 10.1074/jbc.M804665200. Epub 2008 Aug 28. J Biol Chem. 2008. PMID: 18755687 Free PMC article.

8

The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion.

Odegaard ML, Joseph JW, Jensen MV, Lu D, Ilkayeva O, Ronnebaum SM, Becker TC, Newgard CB. Odegaard ML, et al. Among authors: lu d. J Biol Chem. 2010 May 28;285(22):16530-7. doi: 10.1074/jbc.M109.092593. Epub 2010 Mar 31. J Biol Chem. 2010. PMID: 20356834 Free PMC article.

9

Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion.

Jensen MV, Haldeman JM, Zhang H, Lu D, Huising MO, Vale WW, Hohmeier HE, Rosenberg P, Newgard CB. Jensen MV, et al. Among authors: lu d. J Biol Chem. 2013 Aug 9;288(32):23128-40. doi: 10.1074/jbc.M113.491654. Epub 2013 Jun 20. J Biol Chem. 2013. PMID: 23788641 Free PMC article.

10

Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion.

Zhang GF, Jensen MV, Gray SM, El K, Wang Y, Lu D, Becker TC, Campbell JE, Newgard CB. Zhang GF, et al. Among authors: lu d. Cell Metab. 2021 Apr 6;33(4):804-817.e5. doi: 10.1016/j.cmet.2020.11.020. Epub 2020 Dec 14. Cell Metab. 2021. PMID: 33321098 Free PMC article.

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