Pedersen JT - Search Results

1

Affinity capillary electrophoresis for identification and investigation of human Gc-globulin (vitamin D-binding protein) and its isoforms interacting with G-actin.

Pedersen JT, Ostergaard J, Houen G, Heegaard NH. Pedersen JT, et al. Electrophoresis. 2008 Apr;29(8):1723-33. doi: 10.1002/elps.200700618. Electrophoresis. 2008. PMID: 18383011

2

Rapid formation of a preoligomeric peptide-metal-peptide complex following copper(II) binding to amyloid β peptides.

Pedersen JT, Teilum K, Heegaard NH, Østergaard J, Adolph HW, Hemmingsen L. Pedersen JT, et al. Angew Chem Int Ed Engl. 2011 Mar 7;50(11):2532-5. doi: 10.1002/anie.201006335. Epub 2011 Feb 17. Angew Chem Int Ed Engl. 2011. PMID: 21370331 No abstract available.

3

Cu(II) mediates kinetically distinct, non-amyloidogenic aggregation of amyloid-beta peptides.

Pedersen JT, Østergaard J, Rozlosnik N, Gammelgaard B, Heegaard NH. Pedersen JT, et al. J Biol Chem. 2011 Jul 29;286(30):26952-63. doi: 10.1074/jbc.M111.220863. Epub 2011 Jun 3. J Biol Chem. 2011. PMID: 21642429 Free PMC article.

4

Analysis of protein aggregation in neurodegenerative disease.

Pedersen JT, Heegaard NH. Pedersen JT, et al. Anal Chem. 2013 May 7;85(9):4215-27. doi: 10.1021/ac400023c. Epub 2013 Apr 4. Anal Chem. 2013. PMID: 23472885 Review.

5

Rapid exchange of metal between Zn(7)-metallothionein-3 and amyloid-β peptide promotes amyloid-related structural changes.

Pedersen JT, Hureau C, Hemmingsen L, Heegaard NH, Østergaard J, Vašák M, Faller P. Pedersen JT, et al. Biochemistry. 2012 Feb 28;51(8):1697-706. doi: 10.1021/bi201774z. Epub 2012 Feb 10. Biochemistry. 2012. PMID: 22283439

6

Amyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox Silencing.

Pedersen JT, Chen SW, Borg CB, Ness S, Bahl JM, Heegaard NH, Dobson CM, Hemmingsen L, Cremades N, Teilum K. Pedersen JT, et al. J Am Chem Soc. 2016 Mar 30;138(12):3966-9. doi: 10.1021/jacs.5b13577. Epub 2016 Mar 21. J Am Chem Soc. 2016. PMID: 26967463 Free PMC article.

7

Inhibition of Cu-amyloid-β by using bifunctional peptides with β-sheet breaker and chelator moieties.

Jensen M, Canning A, Chiha S, Bouquerel P, Pedersen JT, Østergaard J, Cuvillier O, Sasaki I, Hureau C, Faller P. Jensen M, et al. Among authors: pedersen jt. Chemistry. 2012 Apr 16;18(16):4836-9. doi: 10.1002/chem.201103546. Epub 2012 Mar 15. Chemistry. 2012. PMID: 22422637

8

Nanosecond Dynamics at Protein Metal Sites: An Application of Perturbed Angular Correlation (PAC) of γ-Rays Spectroscopy.

Chakraborty S, Pallada S, Pedersen JT, Jancso A, Correia JG, Hemmingsen L. Chakraborty S, et al. Among authors: pedersen jt. Acc Chem Res. 2017 Sep 19;50(9):2225-2232. doi: 10.1021/acs.accounts.7b00219. Epub 2017 Aug 23. Acc Chem Res. 2017. PMID: 28832106

9

The pKa value and accessibility of cysteine residues are key determinants for protein substrate discrimination by glutaredoxin.

Jensen KS, Pedersen JT, Winther JR, Teilum K. Jensen KS, et al. Among authors: pedersen jt. Biochemistry. 2014 Apr 22;53(15):2533-40. doi: 10.1021/bi4016633. Epub 2014 Apr 9. Biochemistry. 2014. PMID: 24673564

10

Aggregation-Prone Amyloid-β⋅Cu(II) Species Formed on the Millisecond Timescale under Mildly Acidic Conditions.

Pedersen JT, Borg CB, Michaels TC, Knowles TP, Faller P, Teilum K, Hemmingsen L. Pedersen JT, et al. Chembiochem. 2015 Jun 15;16(9):1293-7. doi: 10.1002/cbic.201500080. Epub 2015 May 18. Chembiochem. 2015. PMID: 25989377

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