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Overcoming the genotoxicity of a pyrrolidine substituted arylindenopyrimidine as a potent dual adenosine A(2A)/A(1) antagonist by minimizing bioactivation to an iminium ion reactive intermediate.
Lim HK, Chen J, Sensenhauser C, Cook K, Preston R, Thomas T, Shook B, Jackson PF, Rassnick S, Rhodes K, Gopaul V, Salter R, Silva J, Evans DC. Lim HK, et al. Among authors: cook k. Chem Res Toxicol. 2011 Jul 18;24(7):1012-30. doi: 10.1021/tx1004437. Epub 2011 Jun 28. Chem Res Toxicol. 2011. PMID: 21667953
Evaluating renal disease in pediatric-onset anti-neutrophil cytoplasmic antibody-associated vasculitis: disease course, outcomes, and predictors of outcome.
Toor KK, Chen A, Cabral DA, Mammen C, Bosman ES, Shen Y, Bone JN, Noone D, Al-Abadi E, Benseler S, Berard R, Bohm M, Charuvanij S, Cook K, Dancey P, Deepak S, Duffy C, Eberhard B, Elder M, Foell D, Gerstbacher D, Heshin-Bekenstein M, Huber A, James KE, Kim S, Klein-Gitelman M, Martin N, McErlane F, Moorthy LN, Myrup C, Riley P, Shenoi S, Sivaraman V, Tanner T, Tarvin S, Wagner-Weiner L, Yeung RSM, Brown KL, Morishita KA; PedVas Investigator's Network. Toor KK, et al. Among authors: cook k. Arthritis Rheumatol. 2024 Dec 3. doi: 10.1002/art.43071. Online ahead of print. Arthritis Rheumatol. 2024. PMID: 39624015
1,421 results