Sensenhauser C - Search Results

1

A generic method to detect electrophilic intermediates using isotopic pattern triggered data-dependent high-resolution accurate mass spectrometry.

Lim HK, Chen J, Cook K, Sensenhauser C, Silva J, Evans DC. Lim HK, et al. Among authors: sensenhauser c. Rapid Commun Mass Spectrom. 2008 Apr;22(8):1295-311. doi: 10.1002/rcm.3504. Rapid Commun Mass Spectrom. 2008. PMID: 18383206

2

Metabolite identification by data-dependent accurate mass spectrometric analysis at resolving power of 60,000 in external calibration mode using an LTQ/Orbitrap.

Lim HK, Chen J, Sensenhauser C, Cook K, Subrahmanyam V. Lim HK, et al. Among authors: sensenhauser c. Rapid Commun Mass Spectrom. 2007;21(12):1821-32. doi: 10.1002/rcm.3024. Rapid Commun Mass Spectrom. 2007. PMID: 17497624

3

Overcoming the genotoxicity of a pyrrolidine substituted arylindenopyrimidine as a potent dual adenosine A(2A)/A(1) antagonist by minimizing bioactivation to an iminium ion reactive intermediate.

Lim HK, Chen J, Sensenhauser C, Cook K, Preston R, Thomas T, Shook B, Jackson PF, Rassnick S, Rhodes K, Gopaul V, Salter R, Silva J, Evans DC. Lim HK, et al. Among authors: sensenhauser c. Chem Res Toxicol. 2011 Jul 18;24(7):1012-30. doi: 10.1021/tx1004437. Epub 2011 Jun 28. Chem Res Toxicol. 2011. PMID: 21667953

4

Interleukins-12 and -23 do not alter expression or activity of multiple cytochrome P450 enzymes in cryopreserved human hepatocytes.

Dallas S, Chattopadhyay S, Sensenhauser C, Batheja A, Singer M, Silva J. Dallas S, et al. Among authors: sensenhauser c. Drug Metab Dispos. 2013 Apr;41(4):689-93. doi: 10.1124/dmd.112.048884. Epub 2013 Jan 24. Drug Metab Dispos. 2013. PMID: 23349185

5

Expression and induction potential of cytochromes P450 in human cryopreserved hepatocytes.

Roymans D, Annaert P, Van Houdt J, Weygers A, Noukens J, Sensenhauser C, Silva J, Van Looveren C, Hendrickx J, Mannens G, Meuldermans W. Roymans D, et al. Among authors: sensenhauser c. Drug Metab Dispos. 2005 Jul;33(7):1004-16. doi: 10.1124/dmd.104.003046. Epub 2005 Mar 31. Drug Metab Dispos. 2005. PMID: 15802389

6

De-risking bio-therapeutics for possible drug interactions using cryopreserved human hepatocytes.

Dallas S, Sensenhauser C, Batheja A, Singer M, Markowska M, Zakszewski C, Mamidi RN, McMillia M, Han C, Zhou H, Silva J. Dallas S, et al. Among authors: sensenhauser c. Curr Drug Metab. 2012 Sep 1;13(7):923-9. doi: 10.2174/138920012802138589. Curr Drug Metab. 2012. PMID: 22475265

7

In vitro and physiologically-based pharmacokinetic based assessment of drug-drug interaction potential of canagliflozin.

Mamidi RNVS, Dallas S, Sensenhauser C, Lim HK, Scheers E, Verboven P, Cuyckens F, Leclercq L, Evans DC, Kelley MF, Johnson MD, Snoeys J. Mamidi RNVS, et al. Among authors: sensenhauser c. Br J Clin Pharmacol. 2017 May;83(5):1082-1096. doi: 10.1111/bcp.13186. Epub 2016 Dec 20. Br J Clin Pharmacol. 2017. PMID: 27862160 Free PMC article.

8

Gut-Restricted Selective Cyclooxygenase-2 (COX-2) Inhibitors for Chemoprevention of Colorectal Cancer.

Zhang Z, Ghosh A, Connolly PJ, King P, Wilde T, Wang J, Dong Y, Li X, Liao D, Chen H, Tian G, Suarez J, Bonnette WG, Pande V, Diloreto KA, Shi Y, Patel S, Pietrak B, Szewczuk L, Sensenhauser C, Dallas S, Edwards JP, Bachman KE, Evans DC. Zhang Z, et al. Among authors: sensenhauser c. J Med Chem. 2021 Aug 12;64(15):11570-11596. doi: 10.1021/acs.jmedchem.1c00890. Epub 2021 Jul 19. J Med Chem. 2021. PMID: 34279934

9

Cytochrome P450 induction response in tethered spheroids as a three-dimensional human hepatocyte in vitro model.

Xia L, Hong X, Sakban RB, Qu Y, Singh NH, McMillian M, Dallas S, Silva J, Sensenhauser C, Zhao S, Lim HK, Yu H. Xia L, et al. Among authors: sensenhauser c. J Appl Toxicol. 2016 Feb;36(2):320-9. doi: 10.1002/jat.3189. Epub 2015 Jul 21. J Appl Toxicol. 2016. PMID: 26201057

10

In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity.

Monbaliu J, Gonzalez M, Bernard A, Jiao J, Sensenhauser C, Snoeys J, Stieltjes H, Wynant I, Smit JW, Chien C. Monbaliu J, et al. Among authors: sensenhauser c. Drug Metab Dispos. 2016 Oct;44(10):1682-91. doi: 10.1124/dmd.116.070672. Epub 2016 Aug 8. Drug Metab Dispos. 2016. PMID: 27504016

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