Aubol B - Search Results

1

Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.

Antonysamy SS, Aubol B, Blaney J, Browner MF, Giannetti AM, Harris SF, Hébert N, Hendle J, Hopkins S, Jefferson E, Kissinger C, Leveque V, Marciano D, McGee E, Nájera I, Nolan B, Tomimoto M, Torres E, Wright T. Antonysamy SS, et al. Among authors: aubol b. Bioorg Med Chem Lett. 2008 May 1;18(9):2990-5. doi: 10.1016/j.bmcl.2008.03.056. Epub 2008 Mar 22. Bioorg Med Chem Lett. 2008. PMID: 18400495

2

SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo.

Buchanan SG, Hendle J, Lee PS, Smith CR, Bounaud PY, Jessen KA, Tang CM, Huser NH, Felce JD, Froning KJ, Peterman MC, Aubol BE, Gessert SF, Sauder JM, Schwinn KD, Russell M, Rooney IA, Adams J, Leon BC, Do TH, Blaney JM, Sprengeler PA, Thompson DA, Smyth L, Pelletier LA, Atwell S, Holme K, Wasserman SR, Emtage S, Burley SK, Reich SH. Buchanan SG, et al. Mol Cancer Ther. 2009 Dec;8(12):3181-90. doi: 10.1158/1535-7163.MCT-09-0477. Mol Cancer Ther. 2009. PMID: 19934279

3

Chemical clamping allows for efficient phosphorylation of the RNA carrier protein Npl3.

Aubol BE, Ungs L, Lukasiewicz R, Ghosh G, Adams JA. Aubol BE, et al. J Biol Chem. 2004 Jul 16;279(29):30182-8. doi: 10.1074/jbc.M402797200. Epub 2004 May 15. J Biol Chem. 2004. PMID: 15145958 Free article.

4

Phosphoryl transfer step in the C-terminal Src kinase controls Src recognition.

Lieser SA, Shindler C, Aubol BE, Lee S, Sun G, Adams JA. Lieser SA, et al. J Biol Chem. 2005 Mar 4;280(9):7769-76. doi: 10.1074/jbc.M411736200. Epub 2004 Dec 28. J Biol Chem. 2005. PMID: 15623523 Free article.

5

Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2.

Ngo JC, Chakrabarti S, Ding JH, Velazquez-Dones A, Nolen B, Aubol BE, Adams JA, Fu XD, Ghosh G. Ngo JC, et al. Among authors: aubol be. Mol Cell. 2005 Oct 7;20(1):77-89. doi: 10.1016/j.molcel.2005.08.025. Mol Cell. 2005. PMID: 16209947 Free article.

6

Mechanistic insights into Sky1p, a yeast homologue of the mammalian SR protein kinases.

Aubol BE, Nolen B, Vu D, Ghosh G, Adams JA. Aubol BE, et al. Biochemistry. 2002 Aug 6;41(31):10002-9. doi: 10.1021/bi020233y. Biochemistry. 2002. PMID: 12146964

7

Processive phosphorylation of alternative splicing factor/splicing factor 2.

Aubol BE, Chakrabarti S, Ngo J, Shaffer J, Nolen B, Fu XD, Ghosh G, Adams JA. Aubol BE, et al. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12601-6. doi: 10.1073/pnas.1635129100. Epub 2003 Oct 10. Proc Natl Acad Sci U S A. 2003. PMID: 14555757 Free PMC article.

8

Novel destabilization of nucleotide binding by the gamma phosphate of ATP in the yeast SR protein kinase Sky1p.

Aubol BE, Nolen B, Shaffer J, Ghosh G, Adams JA. Aubol BE, et al. Biochemistry. 2003 Nov 11;42(44):12813-20. doi: 10.1021/bi035200c. Biochemistry. 2003. PMID: 14596595

9

Coupling phosphoryl transfer and substrate interactions in protein kinases.

Lieser SA, Aubol BE, Wong L, Jennings PA, Adams JA. Lieser SA, et al. Biochim Biophys Acta. 2005 Dec 30;1754(1-2):191-9. doi: 10.1016/j.bbapap.2005.07.024. Epub 2005 Sep 8. Biochim Biophys Acta. 2005. PMID: 16213199 Review.

10

Applying the brakes to multisite SR protein phosphorylation: substrate-induced effects on the splicing kinase SRPK1.

Aubol BE, Adams JA. Aubol BE, et al. Biochemistry. 2011 Aug 16;50(32):6888-900. doi: 10.1021/bi2007993. Epub 2011 Jul 15. Biochemistry. 2011. PMID: 21728354 Free PMC article.

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