Barrish JC - Search Results

1

(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1h-1,2,4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid (BMS-644950): a rationally designed orally efficacious 3-hydroxy-3-methylglutaryl coenzyme-a reductase inhibitor with reduced myotoxicity potential.

Ahmad S, Madsen CS, Stein PD, Janovitz E, Huang C, Ngu K, Bisaha S, Kennedy LJ, Chen BC, Zhao R, Sitkoff D, Monshizadegan H, Yin X, Ryan CS, Zhang R, Giancarli M, Bird E, Chang M, Chen X, Setters R, Search D, Zhuang S, Nguyen-Tran V, Cuff CA, Harrity T, Darienzo CJ, Li T, Reeves RA, Blanar MA, Barrish JC, Zahler R, Robl JA. Ahmad S, et al. Among authors: barrish jc. J Med Chem. 2008 May 8;51(9):2722-33. doi: 10.1021/jm800001n. Epub 2008 Apr 15. J Med Chem. 2008. PMID: 18412317

2

Antiviral properties of aminodiol inhibitors against human immunodeficiency virus and protease.

Bechtold CM, Patick AK, Alam M, Greytok J, Tino JA, Chen P, Gordon E, Ahmad S, Barrish JC, Zahler R, et al. Bechtold CM, et al. Among authors: barrish jc. Antimicrob Agents Chemother. 1995 Feb;39(2):374-9. doi: 10.1128/AAC.39.2.374. Antimicrob Agents Chemother. 1995. PMID: 7726501 Free PMC article.

3

Characterization of a human immunodeficiency virus type 1 variant with reduced sensitivity to an aminodiol protease inhibitor.

Patick AK, Rose R, Greytok J, Bechtold CM, Hermsmeier MA, Chen PT, Barrish JC, Zahler R, Colonno RJ, Lin PF. Patick AK, et al. Among authors: barrish jc. J Virol. 1995 Apr;69(4):2148-52. doi: 10.1128/JVI.69.4.2148-2152.1995. J Virol. 1995. PMID: 7884862 Free PMC article.

4

Aminodiol HIV protease inhibitors. 1. Design, synthesis, and preliminary SAR.

Barrish JC, Gordon E, Alam M, Lin PF, Bisacchi GS, Chen P, Cheng PT, Fritz AW, Greytok JA, Hermsmeier MA. Barrish JC, et al. J Med Chem. 1994 Jun 10;37(12):1758-68. doi: 10.1021/jm00038a005. J Med Chem. 1994. PMID: 8021916

5

1-Benzazepin-2-one calcium channel blockers--VI. Receptor-binding model and possible relationship to desmethoxyverapamil.

Kimball SD, Hunt JT, Barrish JC, Das J, Floyd DM, Lago MW, Lee VG, Spergel SH, Moreland S, Hedberg SA, et al. Kimball SD, et al. Among authors: barrish jc. Bioorg Med Chem. 1993 Oct;1(4):285-307. doi: 10.1016/s0968-0896(00)82134-3. Bioorg Med Chem. 1993. PMID: 8081860

6

Conformationally constrained calcium channel blockers: novel mimics of 1-benzazepin-2-ones.

Barrish JC, Spergel SH, Moreland S, Grover G, Hedberg SA, Pudzianowski AT, Gougoutas JZ, Malley MF. Barrish JC, et al. Bioorg Med Chem. 1993 Oct;1(4):309-25. doi: 10.1016/s0968-0896(00)82135-5. Bioorg Med Chem. 1993. PMID: 8081861

7

Interphenylene 7-oxabicyclo[2.2.1]heptane oxazoles. Highly potent, selective, and long-acting thromboxane A2 receptor antagonists.

Misra RN, Brown BR, Sher PM, Patel MM, Hall SE, Han WC, Barrish JC, Kocy O, Harris DN, Goldenberg HJ, et al. Misra RN, et al. Among authors: barrish jc. J Med Chem. 1993 May 14;36(10):1401-17. doi: 10.1021/jm00062a013. J Med Chem. 1993. PMID: 8496908

8

Mutational analysis of the endothelin type A receptor (ETA): interactions and model of selective ETA antagonist BMS-182874 with putative ETA receptor binding cavity.

Webb ML, Patel PS, Rose PM, Liu EC, Stein PD, Barrish J, Lach DA, Stouch T, Fisher SM, Hadjilambris O, Lee H, Skwish S, Dickinson KE, Krystek SR Jr. Webb ML, et al. Biochemistry. 1996 Feb 27;35(8):2548-56. doi: 10.1021/bi951836v. Biochemistry. 1996. PMID: 8611558

9

Aminodiol HIV protease inhibitors. Synthesis and structure-activity relationships of P1/P1' compounds: correlation between lipophilicity and cytotoxicity.

Chen P, Cheng PT, Alam M, Beyer BD, Bisacchi GS, Dejneka T, Evans AJ, Greytok JA, Hermsmeier MA, Humphreys WG, Jacobs GA, Kocy O, Lin PF, Lis KA, Marella MA, Ryono DE, Sheaffer AK, Spergel SH, Sun CQ, Tino JA, Vite G, Colonno RJ, Zahler R, Barrish JC. Chen P, et al. Among authors: barrish jc. J Med Chem. 1996 May 10;39(10):1991-2007. doi: 10.1021/jm950717a. J Med Chem. 1996. PMID: 8642558

10

Biphenylsulfonamide endothelin receptor antagonists. 2. Discovery of 4'-oxazolyl biphenylsulfonamides as a new class of potent, highly selective ET(A) antagonists.

Murugesan N, Gu Z, Stein PD, Spergel S, Mathur A, Leith L, Liu EC, Zhang R, Bird E, Waldron T, Marino A, Morrison RA, Webb ML, Moreland S, Barrish JC. Murugesan N, et al. Among authors: barrish jc. J Med Chem. 2000 Aug 10;43(16):3111-7. doi: 10.1021/jm000105c. J Med Chem. 2000. PMID: 10956219

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

113 results

Search Page

Filters