Dolan PD - Search Results

1

Genetic or pharmacologic amplification of nrf2 signaling inhibits acute inflammatory liver injury in mice.

Osburn WO, Yates MS, Dolan PD, Chen S, Liby KT, Sporn MB, Taguchi K, Yamamoto M, Kensler TW. Osburn WO, et al. Among authors: dolan pd. Toxicol Sci. 2008 Jul;104(1):218-27. doi: 10.1093/toxsci/kfn079. Epub 2008 Apr 15. Toxicol Sci. 2008. PMID: 18417483 Free PMC article.

2

A-ring hydroxymethyl 19-nor analogs of the natural hormone 1alpha,25-dihydroxyvitamin D(3): synthesis and preliminary biological evaluation.

Hatcher MA, Peleg S, Dolan P, Kensler TW, Sarjeant A, Posner GH. Hatcher MA, et al. Bioorg Med Chem. 2005 Jun 2;13(12):3964-76. doi: 10.1016/j.bmc.2005.04.010. Bioorg Med Chem. 2005. PMID: 15878279

3

'Novel alkyl side chain sulfone 1alpha,25-dihydroxyvitamin D3 analogs: a comparison of in vitro antiproliferative activities and in vivo calcemic activities'.

Usera AR, Dolan P, Kensler TW, Posner GH. Usera AR, et al. Bioorg Med Chem. 2009 Aug 1;17(15):5627-31. doi: 10.1016/j.bmc.2009.06.033. Epub 2009 Jun 21. Bioorg Med Chem. 2009. PMID: 19577932 Free PMC article.

4

Novel A-ring analogs of the hormone 1alpha,25-dihydroxyvitamin D3: synthesis and preliminary biological evaluation.

Posner GH, Lee SH, Kim HJ, Peleg S, Dolan P, Kensler TW. Posner GH, et al. Bioorg Med Chem. 2005 Apr 15;13(8):2959-66. doi: 10.1016/j.bmc.2005.02.005. Bioorg Med Chem. 2005. PMID: 15781405

5

Highly antiproliferative, low-calcemic, side-chain amide and hydroxamate analogs of the hormone 1alpha,25-dihydroxyvitamin D3.

Sinishtaj S, Jeon HB, Dolan P, Kensler TW, Posner GH. Sinishtaj S, et al. Bioorg Med Chem. 2006 Sep 15;14(18):6341-8. doi: 10.1016/j.bmc.2006.05.050. Epub 2006 Jun 12. Bioorg Med Chem. 2006. PMID: 16765598

6

Conceptually new low-calcemic oxime analogues of the hormone 1 alpha,25-dihydroxyvitamin D(3): synthesis and biological testing.

Posner GH, Halford BA, Peleg S, Dolan P, Kensler TW. Posner GH, et al. J Med Chem. 2002 Apr 11;45(8):1723-30. doi: 10.1021/jm010560o. J Med Chem. 2002. PMID: 11931627

7

2,2-Disubstituted analogues of the natural hormone 1 alpha,25-dihydroxyvitamin D(3): chemistry and biology.

Posner GH, Woodard BT, Crawford KR, Peleg S, Brown AJ, Dolan P, Kensler TW. Posner GH, et al. Bioorg Med Chem. 2002 Jul;10(7):2353-65. doi: 10.1016/s0968-0896(02)00058-5. Bioorg Med Chem. 2002. PMID: 11983533

8

Highly antiproliferative, low-calcemic, side-chain ketone analogs of the hormone 1alpha,25-dihydroxyvitamin D3.

Posner GH, Kim HJ, Kahraman M, Jeon HB, Suh BC, Li H, Dolan P, Kensler TW. Posner GH, et al. Bioorg Med Chem. 2005 Oct 1;13(19):5569-80. doi: 10.1016/j.bmc.2005.06.031. Bioorg Med Chem. 2005. PMID: 16039132

9

Difluoromethyl analogs of the natural hormone 1alpha,25-dihydroxyvitamin D3: Design, synthesis, and preliminary biological evaluation.

Posner GH, Suh BC, Petersen KS, Dolan P, Agoston ES, Kensler TW, Koh JT, Peleg S. Posner GH, et al. J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):213-21. doi: 10.1016/j.jsbmb.2006.12.024. Epub 2007 Jan 10. J Steroid Biochem Mol Biol. 2007. PMID: 17218093 Free PMC article.

10

Low-calcemic, efficacious, 1alpha,25-dihydroxyvitamin D3 analog QW-1624F2-2: calcemic dose-response determination, preclinical genotoxicity testing, and revision of A-ring stereochemistry.

Posner GH, Jeon HB, Sarjeant A, Riccio ES, Doppalapudi RS, Kapetanovic IM, Saha U, Dolan P, Kensler TW. Posner GH, et al. Steroids. 2004 Oct-Nov;69(11-12):757-62. doi: 10.1016/j.steroids.2004.09.004. Steroids. 2004. PMID: 15579327

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