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Interferon-beta signaling is enhanced in patients with insufficient coronary collateral artery development and inhibits arteriogenesis in mice.
Schirmer SH, Fledderus JO, Bot PT, Moerland PD, Hoefer IE, Baan J Jr, Henriques JP, van der Schaaf RJ, Vis MM, Horrevoets AJ, Piek JJ, van Royen N. Schirmer SH, et al. Among authors: bot pt. Circ Res. 2008 May 23;102(10):1286-94. doi: 10.1161/CIRCRESAHA.108.171827. Epub 2008 Apr 17. Circ Res. 2008. PMID: 18420941
START Trial: a pilot study on STimulation of ARTeriogenesis using subcutaneous application of granulocyte-macrophage colony-stimulating factor as a new treatment for peripheral vascular disease.
van Royen N, Schirmer SH, Atasever B, Behrens CY, Ubbink D, Buschmann EE, Voskuil M, Bot P, Hoefer I, Schlingemann RO, Biemond BJ, Tijssen JG, Bode C, Schaper W, Oskam J, Legemate DA, Piek JJ, Buschmann I. van Royen N, et al. Circulation. 2005 Aug 16;112(7):1040-6. doi: 10.1161/CIRCULATIONAHA.104.529552. Epub 2005 Aug 8. Circulation. 2005. PMID: 16087795 Clinical Trial.
Forkhead box protein P1 as a downstream target of transforming growth factor-β induces collagen synthesis and correlates with a more stable plaque phenotype.
Bot PT, Grundmann S, Goumans MJ, de Kleijn D, Moll F, de Boer O, van der Wal AC, van Soest A, de Vries JP, van Royen N, Piek JJ, Pasterkamp G, Hoefer IE. Bot PT, et al. Atherosclerosis. 2011 Sep;218(1):33-43. doi: 10.1016/j.atherosclerosis.2011.05.017. Epub 2011 May 25. Atherosclerosis. 2011. PMID: 21683954 Free article.
Hyaluronic acid metabolism is increased in unstable plaques.
Bot PT, Pasterkamp G, Goumans MJ, Strijder C, Moll FL, de Vries JP, Pals ST, de Kleijn DP, Piek JJ, Hoefer IE. Bot PT, et al. Eur J Clin Invest. 2010 Sep;40(9):818-27. doi: 10.1111/j.1365-2362.2010.02326.x. Epub 2010 Jul 1. Eur J Clin Invest. 2010. PMID: 20597964
[Congenital thrombocytopenia in adults].
van Zweeden A, Bot P, Smets Y, Terpstra W. van Zweeden A, et al. Ned Tijdschr Geneeskd. 2011;155:A2634. Ned Tijdschr Geneeskd. 2011. PMID: 21382213 Dutch.
15 results