Thomas G - Search Results

1

Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34.

Gulati P, Gaspers LD, Dann SG, Joaquin M, Nobukuni T, Natt F, Kozma SC, Thomas AP, Thomas G. Gulati P, et al. Among authors: thomas g, thomas ap. Cell Metab. 2008 May;7(5):456-65. doi: 10.1016/j.cmet.2008.03.002. Cell Metab. 2008. PMID: 18460336 Free PMC article.

2

The amino acid sensitive TOR pathway from yeast to mammals.

Dann SG, Thomas G. Dann SG, et al. Among authors: thomas g. FEBS Lett. 2006 May 22;580(12):2821-9. doi: 10.1016/j.febslet.2006.04.068. Epub 2006 May 2. FEBS Lett. 2006. PMID: 16684541 Free article. Review.

3

hvps34, an ancient player, enters a growing game: mTOR Complex1/S6K1 signaling.

Nobukuni T, Kozma SC, Thomas G. Nobukuni T, et al. Among authors: thomas g. Curr Opin Cell Biol. 2007 Apr;19(2):135-41. doi: 10.1016/j.ceb.2007.02.019. Epub 2007 Feb 23. Curr Opin Cell Biol. 2007. PMID: 17321123 Review.

4

mTOR Complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer.

Dann SG, Selvaraj A, Thomas G. Dann SG, et al. Among authors: thomas g. Trends Mol Med. 2007 Jun;13(6):252-9. doi: 10.1016/j.molmed.2007.04.002. Epub 2007 Apr 23. Trends Mol Med. 2007. PMID: 17452018 Review.

5

Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner.

Kalender A, Selvaraj A, Kim SY, Gulati P, Brûlé S, Viollet B, Kemp BE, Bardeesy N, Dennis P, Schlager JJ, Marette A, Kozma SC, Thomas G. Kalender A, et al. Among authors: thomas g. Cell Metab. 2010 May 5;11(5):390-401. doi: 10.1016/j.cmet.2010.03.014. Cell Metab. 2010. PMID: 20444419 Free PMC article.

6

Tuberous sclerosis complex tumor suppressor-mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent.

Jaeschke A, Hartkamp J, Saitoh M, Roworth W, Nobukuni T, Hodges A, Sampson J, Thomas G, Lamb R. Jaeschke A, et al. Among authors: thomas g. J Cell Biol. 2002 Oct 28;159(2):217-24. doi: 10.1083/jcb.jcb.200206108. Epub 2002 Oct 28. J Cell Biol. 2002. PMID: 12403809 Free PMC article.

7

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2.

Garami A, Zwartkruis FJ, Nobukuni T, Joaquin M, Roccio M, Stocker H, Kozma SC, Hafen E, Bos JL, Thomas G. Garami A, et al. Among authors: thomas g. Mol Cell. 2003 Jun;11(6):1457-66. doi: 10.1016/s1097-2765(03)00220-x. Mol Cell. 2003. PMID: 12820960 Free article.

8

Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development.

Gangloff YG, Mueller M, Dann SG, Svoboda P, Sticker M, Spetz JF, Um SH, Brown EJ, Cereghini S, Thomas G, Kozma SC. Gangloff YG, et al. Among authors: thomas g. Mol Cell Biol. 2004 Nov;24(21):9508-16. doi: 10.1128/MCB.24.21.9508-9516.2004. Mol Cell Biol. 2004. PMID: 15485918 Free PMC article.

9

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

Nobukuni T, Joaquin M, Roccio M, Dann SG, Kim SY, Gulati P, Byfield MP, Backer JM, Natt F, Bos JL, Zwartkruis FJ, Thomas G. Nobukuni T, et al. Among authors: thomas g. Proc Natl Acad Sci U S A. 2005 Oct 4;102(40):14238-43. doi: 10.1073/pnas.0506925102. Epub 2005 Sep 21. Proc Natl Acad Sci U S A. 2005. PMID: 16176982 Free PMC article.

10

Hypothalamic mTOR signaling regulates food intake.

Cota D, Proulx K, Smith KA, Kozma SC, Thomas G, Woods SC, Seeley RJ. Cota D, et al. Among authors: thomas g. Science. 2006 May 12;312(5775):927-30. doi: 10.1126/science.1124147. Science. 2006. PMID: 16690869

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