Sumithran SP - Search Results

1

N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity.

Dwoskin LP, Wooters TE, Sumithran SP, Siripurapu KB, Joyce BM, Lockman PR, Manda VK, Ayers JT, Zhang Z, Deaciuc AG, McIntosh JM, Crooks PA, Bardo MT. Dwoskin LP, et al. Among authors: sumithran sp. J Pharmacol Exp Ther. 2008 Aug;326(2):563-76. doi: 10.1124/jpet.108.136630. Epub 2008 May 6. J Pharmacol Exp Ther. 2008. PMID: 18460644 Free PMC article.

2

Bupropion inhibits nicotine-evoked [(3)H]overflow from rat striatal slices preloaded with [(3)H]dopamine and from rat hippocampal slices preloaded with [(3)H]norepinephrine.

Miller DK, Sumithran SP, Dwoskin LP. Miller DK, et al. Among authors: sumithran sp. J Pharmacol Exp Ther. 2002 Sep;302(3):1113-22. doi: 10.1124/jpet.102.033852. J Pharmacol Exp Ther. 2002. PMID: 12183670

3

N-n-alkylpyridinium analogs, a novel class of nicotinic receptor antagonists: selective inhibition of nicotine-evoked [3H] dopamine overflow from superfused rat striatal slices.

Grinevich VP, Crooks PA, Sumithran SP, Haubner AJ, Ayers JT, Dwoskin LP. Grinevich VP, et al. Among authors: sumithran sp. J Pharmacol Exp Ther. 2003 Sep;306(3):1011-20. doi: 10.1124/jpet.103.051789. Epub 2003 May 23. J Pharmacol Exp Ther. 2003. PMID: 12766255

4

Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents.

Dwoskin LP, Sumithran SP, Zhu J, Deaciuc AG, Ayers JT, Crooks PA. Dwoskin LP, et al. Among authors: sumithran sp. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1863-7. doi: 10.1016/j.bmcl.2003.10.073. Bioorg Med Chem Lett. 2004. PMID: 15050617

5

Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release.

Crooks PA, Ayers JT, Xu R, Sumithran SP, Grinevich VP, Wilkins LH, Deaciuc AG, Allen DD, Dwoskin LP. Crooks PA, et al. Among authors: sumithran sp. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1869-74. doi: 10.1016/j.bmcl.2003.10.074. Bioorg Med Chem Lett. 2004. PMID: 15050618

6

Introduction of unsaturation into the N-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: effect on affinity and selectivity.

Sumithran SP, Crooks PA, Xu R, Zhu J, Deaciuc AG, Wilkins LH, Dwoskin LP. Sumithran SP, et al. AAPS J. 2005 Aug 29;7(1):E201-17. doi: 10.1208/aapsj070119. AAPS J. 2005. PMID: 16146341 Free PMC article.

7

Identification and synthesis of novel alkaloids from the root system of Nicotiana tabacum: affinity for neuronal nicotinic acetylcholine receptors.

Wei X, Sumithran SP, Deaciuc AG, Burton HR, Bush LP, Dwoskin LP, Crooks PA. Wei X, et al. Among authors: sumithran sp. Life Sci. 2005 Dec 22;78(5):495-505. doi: 10.1016/j.lfs.2005.09.009. Epub 2005 Sep 28. Life Sci. 2005. PMID: 16197964 Review.

8

QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release.

Zheng F, Bayram E, Sumithran SP, Ayers JT, Zhan CG, Schmitt JD, Dwoskin LP, Crooks PA. Zheng F, et al. Among authors: sumithran sp. Bioorg Med Chem. 2006 May 1;14(9):3017-37. doi: 10.1016/j.bmc.2005.12.036. Epub 2006 Jan 20. Bioorg Med Chem. 2006. PMID: 16431111

9

Tris-azaaromatic quaternary ammonium salts: Novel templates as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release.

Zheng G, Sumithran SP, Deaciuc AG, Dwoskin LP, Crooks PA. Zheng G, et al. Among authors: sumithran sp. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6701-6. doi: 10.1016/j.bmcl.2007.10.062. Epub 2007 Oct 22. Bioorg Med Chem Lett. 2007. PMID: 17977723 Free PMC article.

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