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Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease.
Arboleda-Velasquez JF, Manent J, Lee JH, Tikka S, Ospina C, Vanderburg CR, Frosch MP, Rodríguez-Falcón M, Villen J, Gygi S, Lopera F, Kalimo H, Moskowitz MA, Ayata C, Louvi A, Artavanis-Tsakonas S. Arboleda-Velasquez JF, et al. Among authors: tikka s. Proc Natl Acad Sci U S A. 2011 May 24;108(21):E128-35. doi: 10.1073/pnas.1101964108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555590 Free PMC article.
Congruence between NOTCH3 mutations and GOM in 131 CADASIL patients.
Tikka S, Mykkänen K, Ruchoux MM, Bergholm R, Junna M, Pöyhönen M, Yki-Järvinen H, Joutel A, Viitanen M, Baumann M, Kalimo H. Tikka S, et al. Brain. 2009 Apr;132(Pt 4):933-9. doi: 10.1093/brain/awn364. Epub 2009 Jan 27. Brain. 2009. PMID: 19174371 Free PMC article.
CADASIL and CARASIL.
Tikka S, Baumann M, Siitonen M, Pasanen P, Pöyhönen M, Myllykangas L, Viitanen M, Fukutake T, Cognat E, Joutel A, Kalimo H. Tikka S, et al. Brain Pathol. 2014 Sep;24(5):525-44. doi: 10.1111/bpa.12181. Brain Pathol. 2014. PMID: 25323668 Free PMC article. Review.
Differences in proliferation rate between CADASIL and control vascular smooth muscle cells are related to increased TGFβ expression.
Panahi M, Yousefi Mesri N, Samuelsson EB, Coupland KG, Forsell C, Graff C, Tikka S, Winblad B, Viitanen M, Karlström H, Sundström E, Behbahani H. Panahi M, et al. Among authors: tikka s. J Cell Mol Med. 2018 Jun;22(6):3016-3024. doi: 10.1111/jcmm.13534. Epub 2018 Mar 13. J Cell Mol Med. 2018. PMID: 29536621 Free PMC article.
Autophagy-lysosomal defect in human CADASIL vascular smooth muscle cells.
Hanemaaijer ES, Panahi M, Swaddiwudhipong N, Tikka S, Winblad B, Viitanen M, Piras A, Behbahani H. Hanemaaijer ES, et al. Among authors: tikka s. Eur J Cell Biol. 2018 Nov;97(8):557-567. doi: 10.1016/j.ejcb.2018.10.001. Epub 2018 Oct 22. Eur J Cell Biol. 2018. PMID: 30392756
136 results